Synthesis of Substituted Naphthalenes by 1,4-Palladium Migration Involved Annulatlon w,th Internal Alkynes  

作　　者：Dong Wei Tian-Jiao Hu Chen-Guo Feng Guo-Qiang Lin 

机构地区：[1]School of Physical Science and Technology, ShanghaiTech University, Shanghai 200031, China [2]Key Laboratory of Synthetic Chemistry of Natural Substances, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200032, China [3]Innovation Research Institute of Traditional Chinese Medicine, Shanghai Uni- versity of Traditional Chinese Medicine, Shanghai 201203, China

出　　处：《Chinese Journal of Chemistry》2018年第8期743-748,共6页中国化学（英文版）

基　　金：Financial support from the National Natural Science Foundation of China （Nos. 21472212, 21572253, 21772216）, the Strategic Priority Research Program of the Chinese Academy of Sciences （No. XDB 20020100） and the Key Research Program of Frontier Science （No.QYZDY-SSW-SLH026） is acknowledged.

摘　　要：The palladium catalyzed annulation of 1-bromo-2-vinylbenzene derivatives with internal alkynes was realized for the efficient synthesis of substituted naphthalenes. A controllable aryl to vinylic 1,4-palladium migration process is the key for success.The palladium catalyzed annulation of 1-bromo-2-vinylbenzene derivatives with internal alkynes was realized for the efficient synthesis of substituted naphthalenes. A controllable aryl to vinylic 1,4-palladium migration process is the key for success.

关 键 词：metal migration NAPHTHALENE PALLADIUM ANNULATION ALKYNE 

分 类 号：O625.322[理学—有机化学] S965.224[理学—化学]