长效驱蚊软膏的制备及驱蚊效果评价  

Development and evaluation on long acting mosquito repellent ointment

作　　者：王佳琳 云超 曾令军[1] 陶春[1] 宋洪涛[1] WANG Jia-lin;YUN Chao;ZENG Ling-jun;TAO Chun;SONG Hong-tao(Fuzhou General Hospital of Nanfiag Command,PLA,Fuzhou 350025,Fufian Province,China;College of Pharmacy,Fujian Medical University)

机构地区：[1]南京军区福州总医院药学科,福建福州350025 [2]福建医科大学药学院,福州350108

出　　处：《中国媒介生物学及控制杂志》2018年第4期400-402,共3页Chinese Journal of Vector Biology and Control

基　　金：福州总医院军民融合研究专项(2017J04)~~

摘　　要：目的评价自制长效驱蚊软膏的缓释性能及其对蚊虫的驱避效果。方法实验用白纹伊蚊采自福建省福州总医院动物房,采集时间为春夏季节16:00-05:00。参照GB/T 13917.9-2009《农药登记用卫生杀虫剂室内药效试验及评价》在室内进行蚊虫驱避效能测试,以挥发率评价长效驱蚊软膏的缓释性能,计算3种驱蚊制剂的驱避效果和平均保护时间。结果自制驱蚊软膏的缓释性能优于市售第二军医大学驱蚊霜,缓释时间长达12 h。避蚊胺酊剂、市售第二军医大学驱蚊霜和自制驱蚊软膏的有效保护时间分别为(3.98±1.14)、(9.78±2.38)和(10.11±2.22)h。结论自制驱蚊软膏的驱避效果优于避蚊胺酊剂和市售第二军医大学驱蚊霜,为长效安全广谱驱避制剂的制备提供理论指导。Objective To develop the long-acting mosquito repellent ointment and evaluate its slow-release performance and repellent effect on mosquitoes.Methods The mosquito Aedes albopictus was collected from the animal sheds of Fuzhou General Hospital of Fujian province during hours of 16：00-05：00 during spring and summer.The sustained release properties of long acting mosquito repellent ointment were evaluated by the percentage of volatile residue.Indoor test was carried out by national method＂GB/T 13917.9-2009 laboratory efficacy test and evaluation of sanitary insecticides for pesticide registration＂,and the repellent effect and average protection time of mosquitoes were calculated.Results The homemade mosquito repellent ointment released DEET faster than the commercially available mosquito repellent cream by The Second Military Medical University,but it could also sustained releasing up to 12 h.The average indoor protection time of the DEET tincture was（3.98±1.14）h,the average indoor mean protection time of a commercially available mosquito repellent cream by The Second Military Medical University was（9.78±2.38）h,the average time for the protection of homemade mosquito repellent ointment was（10.11 ± 2.22）h.Conclusion The selfmade mosquito repellent ointment was better than the DEET tincture and the commercially available mosquito repellent cream by The Second Military Medical University.

关 键 词：蚊类 驱避剂 驱蚊软膏 评价 

分 类 号：R384.1[医药卫生—医学寄生虫学]