习惯性流产患者抗精子抗体、抗子宫内膜抗体和抗心磷脂抗体检测  

Role of antisperm antibody, antiendometrial antibody and anticardiolipin antibody in the process of habitual abortion

作　　者：张展[1] 贾莉婷[1] 杨丽珍[1] 刘东峰[1] 

机构地区：[1]郑州大学第三附属医院检验科,郑州450052

出　　处：《郑州大学学报（医学版）》2002年第5期640-641,共2页Journal of Zhengzhou University(Medical Sciences)

摘　　要：目的 :探讨免疫因素抗精子抗体 (AsAb)、抗子宫内膜抗体 (EmAb)和抗心磷脂抗体 (ACL)在习惯性流产发病中的作用。方法 :采用凝集试验和ELISA方法对 335例习惯性流产患者和 40名正常对照者的血清AsAb、EmAb和ACL进行检测。结果 :习惯性流产组AsAb、EmAb和ACL的总阳性率分别为 9.85 %、40 .59%和2 5 .0 7% ,均高于正常对照组 (分别为 5 .0 % ,5 .0 % ,0 % ) (P <0 .0 5)。结论 :EmAb和ACL在习惯性流产的发病中可能起一定作用 ;Aim:To study the role of immune factor, antisperm antibody (AsAb), antiendometrial antibody (EmAb), anticardiolipin antibody (ACL) in habitual abortion(HA). Methods: Serum AsAb was measured by agglutination and serum EmAb and ACL were measured by ELISA in 335 women with HA and 40 normal women. Results: The total positive rate of serum AsAb, EmAb and ACL in study group were 9.85% , 40.59% and 25.07%, which were significantly higher than that of control group (5.0%,5.0% and 0%) ( P <0.05) . Conclusion: Serum EmAb and ACL play an important role in the process of HA. Serum AsAb suggests that immunological function is disorder in patients with HA.

关 键 词：习惯性流产 抗精子抗体 抗子宫内膜抗体 抗心磷脂抗体 

分 类 号：R714.21[医药卫生—妇产科学]