阿托伐他汀联合黄连素对糖尿病合并脑梗死患者治疗效果的临床分析  

Clinical Effect of Atorvastatin Combined with Berberine in the Treatment of Diabetic Patients with Cerebral Infarction

作　　者：游军 YOU Jun(Huangshi Xisai District Hekou Health Center,Huangshi,Hubei Province,435000 China)

机构地区：[1]湖北黄石市西塞山区河口卫生院,湖北黄石435000

出　　处：《糖尿病新世界》2018年第10期6-8,共3页Diabetes New World Magazine

摘　　要：目的探讨对糖尿病伴有脑梗死患者选择阿托伐他汀+黄连素进行治疗后获得的临床效果。方法选择该院2015年7月—2017年9月收治的92例糖尿病伴有脑梗死患者作为实验对象;采用抽签法分组;研究治疗药物期间,对照组(46例):采用阿托伐他汀药物进行治疗;观察组(46例):采用阿托伐他汀+黄连素进行治疗;最终就两组糖尿病伴有脑梗死患者治疗总有效率、餐后2 h血糖水平、空腹血糖水平、糖化血红蛋白水平以及神经功能缺损程度评分展开对比。结果同对照组糖尿病伴有脑梗死患者治疗总有效率(73.91%)对比,观察组(97.83%)获得明显提升(P<0.05);同对照组糖尿病伴有脑梗死患者餐后2 h血糖水平、空腹血糖水平以及糖化血红蛋白水平对比,观察组获得明显改善(P<0.05);同对照组糖尿病患者神经功能缺损程度评分对比,观察组获得明显改善(P<0.05)。结论医疗人员对于糖尿病伴有脑梗死患者选择阿托伐他汀+黄连素进行治疗,在提高治疗总有效率、改善餐后2 h血糖水平、空腹血糖水平、糖化血红蛋白水平以及改善神经功能缺损程度方面获得理想效果,从而促进糖尿病伴有脑梗死患者的病情康复。Objective To investigate the clinical effect of atorvastatin＋berberine treatment in patients with diabetes complicated with cerebral infarction. Methods A total of 92 patients with diabetes complicated with cerebral infarction who were admitted to the hospital from July 2015 to September 2017 were selected as the experimental subjects. The patients were grouped by the lottery method. During the treatment of the drug, the control group（46 patients） was treated with atorvastatin drugs. The observation group（46 cases）： treatment with atorvastatin ＋ berberine; the final two groups of diabetic patients with cerebral infarction treatment total effective rate, 2 h postprandial blood glucose levels, fasting blood glucose levels, glycated hemoglobin levels and neurological deficit scores were compared. Results Compared with the control group, the total effective rate of treatment（73.91%） in patients with cerebral infarction with diabetes, the observation group（97.83%） was significantly improved（P〈0.05）; with the control group of diabetic patients with cerebral infarction 2 h postprandial blood glucose levels,the fasting blood glucose level and the level of glycated hemoglobin were significantly improved in the observation group（P〈0.05）.Compared with the control group, the neurological deficit degree scores in the diabetic group were significantly improved（P〈0.05）. Conclusion Medical staff selected atorvastatin plus berberine for treatment of patients with diabetes and cerebral infarction, and improved the total effective rate, postprandial blood glucose level, fasting blood glucose level, glycosylated hemoglobin level, and neurological deficits, to promote the recovery of diabetic patients with cerebral infarction.

关 键 词：阿托伐他汀 黄连素 糖尿病 脑梗死 治疗效果 

分 类 号：R587.1[医药卫生—内分泌] R743.33[医药卫生—内科学]