精子获能的研究进展  

Advances in Sperm Capacitation

作　　者：陆金春[1] 张福泉[2] 黄宇烽[1] 张锡然[3] 

机构地区：[1]南京军区南京总医院生殖遗传研究室,江苏,南京,210002 [2]武警南京医院检验科,江苏,南京,210024 [3]南京师范大学生命科学学院,江苏,南京,210097

出　　处：《中华男科学杂志》2002年第4期295-298,共4页National Journal of Andrology

摘　　要：精卵融合之前精子必须获能。获能曾被定义为精子活动亢进 ,但目前认为精子活动亢进可能为精子获能的一个方面或精子获能的结果 ,两者并不完全一致。目前 ,研究精子获能的方法主要有 :体外授精 ,顶体反应的诱导 ,金霉素荧光分析法和麦胚凝集素、植物血凝素荧光分析法。精子获能的体外研究主要集中于对诱导精子获能的物质和诱导后结果的分析 。Sperm must be capacitated before sperm ovum fusion.Capacitation was once considered as hyperactivation.But now many investigators thought that capacitation wasn't equal to hyperactivation, and that sperm hyperactivation might be a moiety of capacitation or the result of capacitation.In the present, the methods used to study sperm capacitation include fertilization in vitro , induction of sperm acrosome reaction, FITC labelled chlortetracycline and plant hemoagglutinin.The studies on sperm capacitation in vitro mainly focused on the inductive substances of sperm capacitation and subsequent results analysis.It could lay foundation for the manifestation of molecular mechanism of sperm capacitation and destination of sperm capacitation in molecular levels.

关 键 词：精子 获能 分子机制 活动亢进 

分 类 号：R321.1[医药卫生—人体解剖和组织胚胎学]