血压变异性及其与靶器官损伤的关系  

Relationship between blood pressure variability and target organ damage

作　　者：李科 王莉[1,2] 刘剑雄 LI Ke;WANG Li;LIU Jian-xiong(Graduate School,Zunyi Medical University,Guizhou Province,Zunyi 563003,China;Department of Cardiology,the Second People＇s Hospital of Chengdu City,Zunyi Medical University,Sichuan Province,Chengdu 610017,China)

机构地区：[1]遵义医学院研究生院,贵州遵义563003 [2]遵义医学院附属成都市第二人民医院心内科,四川成都610017

出　　处：《中国当代医药》2018年第23期30-33,共4页China Modern Medicine

基　　金：四川省科学技术厅科技惠民技术研发项目(2014SZ0240);四川省成都市科技惠民项目(2014-HM01-00349-SF)

摘　　要：高血压是多种心血管疾病的危险因素,部分患者血压控制良好情况下仍然有靶器官受损,发生心血管不良事件,2013年ESC提出血压变异性应成为血压控制领域的一个新的重要靶点。高血压是心、脑、肾等多种靶器官损伤的危险因素,血压变异性作为高血压管控新的靶点,进一步控制血压变异性将有效降低全身重要靶器官的损伤率,降低包括肾功能不全、脑卒中、认知能力下降、心室肥厚、心力衰竭、心律失常、外周动脉硬化及冠心病等疾病发生率。Hypertension is a risk factor for many cardiovascular diseases. In some patients with well-controlled blood pressure, damages of target organs and cardiovascular adverse events may still occur. In 2013, ESC proposed that blood pressure variability should become a new important target in the field of blood pressure control. Hypertension is a risk factor for various target organ damages such as heart, brain and kidney. Blood pressure variability is a new target for the management of hypertension, and further control of blood pressure variability will effectively reduce the damage rate of important target organs throughout the body, as well as reduce the incidence rates of diseases including renal insufficiency, stroke, cognitive decline, ventricular hypertrophy, heart failure, arrhythmia, peripheral arteriosclerosis, and coronary heart disease.

关 键 词：血压变异性 心血管 脑 肾脏 靶器官损伤 关系 

分 类 号：R544.1[医药卫生—心血管疾病]