高血压伴良性前列腺增生的高龄患者24小时动态血压与下尿路症状相关性  

Correlation between 24-hour ambulatory blood pressure and lower urinary tract symptoms in elderly patients with hypertension and benign prostatic hyperplasia

作　　者：陈钰[1] 李建中[1] 浦剑虹[1] 刘海燕[1] 陆金花[1] CHEN Yu, LI Jianzhong, PU Jianhong, LIU Haiyan, LU Jinhua(The First Affiliated Hospital of Soochow University, Suzhou 215006, China)

机构地区：[1]苏州大学附属第一医院,江苏苏州215006

出　　处：《山东医药》2018年第31期78-80,共3页Shandong Medical Journal

摘　　要：目的分析高龄高血压伴良性前列腺增生(BPH)患者24小时动态血压与下尿路症状的相关性。方法79例高龄高血压伴BPH患者,采用无创性携带式动态血压仪监测24小时动态血压,前列腺B超检查计算前列腺体积,并评估其国际前列腺症状评分(IPSS,进一步细分为储尿期症状评分和排尿期症状评分)。Pearson双变量相关性分析法分析24小时动态血压与IPSS评分、储尿期症状评分、排尿期症状评分的相关性。结果 79例患者24 h平均收缩压(24h-s BP)、24 h平均舒张压(24h-d BP)、白昼平均收缩压(d-s BP)、白昼平均舒张压(d-d BP)、夜间平均收缩压(n-s BP)、夜间平均舒张压(n-d BP)分别为(134.6±13.4)、(71.7±6.8)、(135.0±13.9)、(72.4±8.0)、(131.8±15.3)、(68.3±8.7)mm Hg,79例患者IPSS评分为(15.9±8.9)分,其中储尿期症状评分、排尿期症状评分分别为(11.3±7.7)、(7.6±5.8)分。老年高血压合并BPH患者储尿期症状评分与24 h-s BP、n-s BP呈正相关(r=0.352,0.396;P均<0.05),前列腺体积与n-s BP呈正相关(r=0.276,P<0.05)。血压控制不佳者(24 hs BP≥130 mm Hg)储尿期症状评分、夜尿次数均大于血压控制良好者(24 h-s BP<130 mm Hg)(P均<0.05)。结论高龄高血压伴BPH患者24h-s BP、n-s BP与储尿期症状有关。控制血压可改善高龄高血压伴BPH患者的储尿期症状。Objective To analyze the correlation between 24-hour ambulatory blood pressure and lower urinary tract symptoms in elderly patients with hypertension and benign prostatic hyperplasia（BPH）. Methods Seventy-eight aged（≥80 years old） patients with hypertension and BPH were tested for 24-hour ambulatory blood pressure with a noninvasive portable ambulatory blood pressure instrument. The prostate volume was calculated by prostatic ultrasound and International Prostate Symptom Score（IPSS,further subdivided into urine storage period symptom score and voiding period symptom score）. Pearson bivariate correlation analysis was used to analyze the correlation between 24-hour ambulatory blood pressure and IPSS score,urine storage period symptom score and voiding period symptom score. Results The 24 h-mean systolic blood pressure（24 h-s BP）,24 h-mean diastolic blood pressure（24 h-d BP）,daytime mean systolic blood pressure（d-s BP）,daytime mean diastolic blood pressure（d-d BP）,night mean systolic blood pressure（n-s BP）,and night mean diastolic blood pressure（n-d BP） in 79 patients were（134. 6 ± 13. 4）,（71. 7 ± 6. 8）,（135. 0 ± 13. 9）,（72. 4 ± 8. 0）,（131. 8 ± 15. 3）,and（68. 3 ± 8. 7） mm Hg. The IPSS of 79 patients was（15. 9 ± 8. 9）,and the urine storage period symptom score and voiding period symptom score were 11. 3 ± 7. 7 and 7. 6 ± 5. 8,respectively. In the elderly hypertensive patients with BPH,the urine storage period symptom score was positively correlated with 24 h-s BP and n-s BP（r = 0. 352,0. 396; both P〈0. 05）,and the prostate volume was positively correlated with n-s BP（r = 0. 276,P〈0. 05）. The urine storage period symptom score and the number of nocturia were higher in patients with poor blood pressure control（24 h-s BP≥130 mm Hg） were greater than those with good blood pressure control（24 h-s BP 130 mm Hg）（P〈0. 05）. Conclusion The 24 h-s BP and n-s BP in elderly hypertensive patients with BPH is related to the urine

关 键 词：高血压 良性前列腺增生 24小时动态血压 国际前列腺症状评分 

分 类 号：R592[医药卫生—老年医学]