黄芩素对LPS诱导RIMECs损伤的作用效果  

Effect of Baicalein on LPS-induced RIMECs Injury

作　　者：高洋[1] 穆祥[2] GAO Yang;MU Xiang(Huairou Agriculture Bureau of Beijing,Beijing 101400,China;Beijing University of Agriculture,Beijing 102206,China)

机构地区：[1]北京市怀柔区农业局,北京101400 [2]北京农学院,北京102206

出　　处：《黑龙江农业科学》2018年第8期78-81,共4页Heilongjiang Agricultural Sciences

摘　　要：为探究黄芩素的抗内毒素作用,利用MTT法,观察不同浓度黄芩素对细菌脂多糖(LPS)致肠黏膜微血管内皮细胞(RIMECs)损伤的作用效果。结果表明:LPS对RIMVECs增殖的抑制作用显著,而黄芩素对LPS诱导的RIMVECs损伤均均有一定的预防和治疗作用,细胞增殖率升高,且呈剂量依赖关系。In order to explore the anti-endotoxin effect of baicalein,in this study,MTT method was used to observed the effects of baicalein with different concentrations on injury of intestinal mucosal microvascular endothelial cells（RIMECs）induced by lipopolysaccharide（LPS）.The results showed that baicalin had some preventive and therapeutic effects on injury of RIMVECs induced by LPS,and the cell proliferation rate was increased in a dose-dependent manner.

关 键 词：肠黏膜微血管内皮细胞 细菌脂多糖 黄芩素 

分 类 号：R285.5[医药卫生—中药学]