CT及MRI灌注成像对颅内血管外皮细胞瘤和脑膜瘤的鉴别诊断价值  

Differential diagnostic value of CT and MRI perfusion imaging in intracranial hemangiopericytoma and meningioma

作　　者：单奔 柳勇 赵正宇 魏玲 韩雷 周寒松 Ben Shan;Yong Liu;Zheng-yu Zhao;Ling Wei;Lei Han;Han-song Zhou(Department of Radiolog;Huai ＇an Hospital Affiliated to Xuzhou Medical University,Huaian,Jiangsu 223001,China)

机构地区：[1]徐州医科大学附属淮安医院影像科,江苏淮安223001

出　　处：《中国现代医学杂志》2018年第24期114-118,共5页China Journal of Modern Medicine

摘　　要：目的探讨CT及MRI灌注成像在鉴别颅内血管外皮细胞瘤(HPC)和脑膜瘤中的价值。方法回顾性分析经手术病理证实行灌注成像检查的14例HPC患者(HPC组)和42例脑膜瘤患者(脑膜瘤组),统计分析两者影像形态学及灌注成像参数的差异。结果 7例HPC和25例脑膜瘤患者行CT平扫及CTP检查,7例HPC和17例脑膜瘤患者行MRI常规及PWI检查。64.3%(9/14)的HPC和11.9%(5/42)的脑膜瘤呈分叶状生长(χ2=12.698,P=0.000);其他影像形态学比较,差异无统计学意义(P>0.05)。灌注成像HPC组局部脑血流量(RCBF)、局部脑血容量(RCBV)及Rr CBV高于脑膜瘤组(P<0.05);两组平均通过时间比值(RMTT)和达峰时间比值(RTTP)比较,差异无统计学意义(P>0.05)。结论颅内HPC和脑膜瘤影像形态学有较大重叠,但灌注成像参数方面有差异,CT及MRI灌注成像有助于提高颅内HPC术前诊断率。Objective To investigate the value of CT and MRI perfusion imaging in differentiating intracranial hemangiopericytoma （HPC） and meningioma. Methods A retrospective analysis of 14 patients with HPC and 42 patients with meningioma confirmed by operation and pathology was performed. The imaging morphological and perfusion parameters of them were analyzed statistically. Results Routine CT scan and CT perfusion were performed in 7 cases of HPC and 25 cases of meningioma, 7 cases of HPC and 17 cases of meningioma underwent routine MR and perfusion weighted imaging （PWI）. Totally 64.3% （9/14） of HPCs and 11.9% （5/42） of meningiomas were lobulated, the difference was statistically significant （χ2 = 12.698, P = 0.000）. RCBF （t = 3.649, P = 0.001）, RCBV （t = 2.570, P = 0.015） and RrCBV （t = 2.907, P = 0.008） in perfusion imaging of HPCs were significantly higher than those of meningiomas, while RMTT and RTTP did not differ significantly. Conclusion Intracranial HPC and meningioma overlap a lot in imaging morphology, but there are significant differences in perfusion imaging parameters; CT and MRI perfusion imaging can help to improve the preoperative diagnosis rate of HPC.

关 键 词：灌注 血管外皮细胞瘤 脑膜瘤 鉴别 

分 类 号：R814.4[医药卫生—影像医学与核医学]