吸烟与冠心病患者血浆同型半胱氨酸水平的关系  

Relationship between smoking and plasma homocysteine level in coronary heart disease

作　　者：陈景连[1] 吴燕仁 苏瑞文[1] 简忠艳 CHEN Jing-lian;WU Yan-ren;SU Rui-wen;JIAN Zhong-yan(Laboratory Department,Guangdong Agricultural Reclamation Center Hospital,Zhanjiang 524002,China)

机构地区：[1]广东省农垦中心医院检验科,广东湛江524002

出　　处：《广东医科大学学报》2018年第2期166-168,共3页Journal of Guangdong Medical University

摘　　要：目的了解冠心病患者中吸烟与血浆同型半胱氨酸(HCY)的关系。方法采用循环酶速率法检测299例冠心病患者(吸烟144例,不吸烟155例)及137例正常对照者(吸烟69例,不吸烟68例)血浆HCY水平。结果冠心病组、吸烟者血浆HCY水平明显高于对照者、不吸烟者(P<0.01)。除冠心病吸烟组女性血浆HCY水平显著高于男性外(P<0.05),其他各组性别间差异无统计学意义(P>0.05)。结论吸烟可能引起冠心病患者血浆HCY水平升高。Objective To investigate the relationship between smoking and plasma homocysteine level in patients with coronary heart disease（CHD）. Methods Plasma homocysteine content was measured by cyclic enzyme rate method in 299 CHD patients（smoking, 144; non-smoking, 155） and 137 healthy controls（smoking, 69; non-smoking, 68）. Results Plasma homocysteine level was higher in CHD group and smokers than in control group and non-smokers（P〈0.01）. Plasma homocysteine level was increased in females compared with males in smoking CHD group（P〈0.05）, but there was no gender difference in non-smoking CHD and control groups（P〈0.05）. Conclusion Smoking may contribute to the incremental plasma HCY level in CHD patients.

关 键 词：冠心病 吸烟 同型半胱氨酸 

分 类 号：R541.4[医药卫生—心血管疾病]