产前MRI、US检查对胎儿中枢神经系统畸形的诊断效果比较  

Comparison of prenatal MRI and US examination in the diagnosis of fetal central nervous system malformation

作　　者：曾浩 彭敏[2] ZENG Hao;PENG Min(Dept of Radiology,Guangyuan Traditional Chinese Medicine Hospital,Guangyuan 628000,China;Dept of Gynecology,Guangyuan Central Hospital,C-uangyuan 628000,China)

机构地区：[1]广元市中医医院放射科,四川广元628000 [2]广元市中心医院妇产科,四川广元628000

出　　处：《中国实验诊断学》2018年第8期1299-1302,共4页Chinese Journal of Laboratory Diagnosis

基　　金：国家自然科学基金(NO:30670763)资助

摘　　要：目的探讨产前MRI、US检查对胎儿中枢神经系统畸形的诊断效果,帮助临床优化诊断。方法对我院2017年2月-2017年10月期间收治56例孕妇行产前常规MRI和US检查,临床诊断金标准(42例胎儿引产尸检和14例分娩后MRI检查)证实中枢神经系统31例共37处畸形。结合产前US和MRI影像分析,重点比较2种检查手段的诊断效果。结果金标准确诊37处中枢神经系统畸形中,产前MRI正确诊断33例,误诊2例,漏诊2例,正确诊断率89.19%(33/37);产前US正确诊断25例,误诊8例,漏诊4例,正确诊断率67.57%(25/37)。产前US诊断准确率较US高,差异具有统计学意义(P<0.05)。结论产前MRI检查能提供更为全面、可靠的胎儿颅脑结构信息,可作为常规US检查的一种优化补充手段,对降低误诊漏诊风险、指导妊娠结局等意义显著。Objective To explore the diagnostic effect of prenatal MRI and US examination on fetal central nervous system malformation,and to help the clinical optimization of diagnosis.Methods 56 cases of pregnant women in our hospital in February 2017-2017 October were selected for prenatal routine US and MRI examination.The gold standard of clinical diagnosis（42 fetuses induced autopsy and 14 cases of MRI after childbirth）confirmed 31 cases of central nervous system in 37 cases.Combined with prenatal MRI and US imaging analysis,the diagnostic results of the 2 methods were compared.Results 37 cases of central nervous system malformation were diagnosed by gold standard.33 cases were diagnosed correctly by prenatal MRI,2 cases were misdiagnosed,2 cases were missed diagnosis,the correct diagnosis rate was 89.19%（33/37）,25 cases were diagnosed correctly by prenatal US,8 cases were misdiagnosed,4 cases were missed diagnosis,and the correct diagnosis rate was 67.57%（25/37）.The diagnostic accuracy of prenatal US was higher than that of US,and the difference was statistically significant（P〈0.05）.Conclusion prenatal MRI examination can provide more comprehensive and reliable information for fetal cranial structure.It can be used as a supplementary supplement to routine US examination.It has significant significance in reducing misdiagnosis and missed diagnosis and guiding pregnancy outcome.

关 键 词：中枢神经系统 胎儿 畸形 产前检查 MRI 

分 类 号：R726.2[医药卫生—儿科]