快捻久留针刺法对后循环缺血性眩晕大鼠的治疗作用分析  

Effect Analysis of Fast Rotating-Long Retaining Acupuncture on Vertigo Rats with Posterior Circulation Ischemia

作　　者：董永书[1] 行书丽 周红艳[1] 张薇[1] 孙为[1] 范军铭[1] DONG Yongshu;XING Shuli;ZHOU Hongyan;ZHANG Wei;SUN Wei;FAN Junming(Henan Provirvc.e Chinese Medicine Research Institute,Zhengzhou 450000,China;Henan Medical College,Zhengzhou 450000,China)

机构地区：[1]河南省中医药研究院,河南郑州450000 [2]河南医学高等专科学校,河南郑州450000

出　　处：《针灸临床杂志》2018年第8期66-69,共4页Journal of Clinical Acupuncture and Moxibustion

基　　金：河南省科技攻关计划项目;编号:152102310167;河南省中医临床学科领军人才项目;编号:2013-10;河南省公益预研项目;编号:1303511

摘　　要：目的:从大鼠行为学和前庭神经核血流量变化角度研究快捻久留针刺法对后循环缺血性眩晕大鼠的治疗作用。方法:将健康SD大鼠采用手术结扎右侧颈总动脉(CCA)和右侧锁骨下动脉(SCA)的方式建立后循环缺血眩晕大鼠模型。将造模成功后的大鼠随机分为模型组、药物组、普通针刺组和快捻久留针刺组,并设置假手术组做为对照。药物组给予盐酸氟桂利嗪(0.153 mg/ml)灌胃;两针刺组均选取"百会""率谷""风池"穴进行治疗,普通针刺组给予常规针刺;快捻久留针刺组给予快速捻转并长久留针刺激,治疗频率均为每天1次,治疗时间均为10天。观察大鼠一般行为学、旋转刺激后跳台潜伏期、前庭神经核局部血流变化、平衡性等情况。结果:与假手术组比较,造模成功的大鼠前庭神经核局部血流量明显下降、跳台潜伏期明显延长、平衡性下降明显(P<0.05);与模型组相比,两针刺组及药物组均能显著增加大鼠前庭神经核的血流量、缩短跳台潜伏期(P<0.05),快捻久留针刺组疗效更为显著(P<0.01)。在平衡性的检测中,快捻久留针刺组未表现出疗效优势。结论:快捻久留针刺法能有效改善缺血性大鼠的前庭供血,缓解眩晕症状,疗效显著。Objective： To evaluate the effects of fast rotating-long retaining acupuncture on behavioral changes and on blood flow of nuclei vestibularis in rats with vertigo due to posterior circulation ischemia. Methods： The rat model of ischemic vertigo was induced by ligaturing the right common carotid artery（ CCA） and subclavianartery（ SCA）. The successful models were randomly divided into the model group,the medication group,the common acupuncture group,as well as the fast rotating-long retaining acupuncture group; the sham operation group was taken as the control. The medication group was given Flunarizine hydrochloride solution（ 0. 153 mg/ml）. Points chosen in the two acupuncture groups were Baihui（ GV20）,Shuaigu（ GB8） and Fengchi（ GB20）,the treatment was once per day for ten days. The general behavior of rats,step down latency（ SDL） after rotation stimulation,the blood flow changes of the vestibular nucleus,and the body balance of the rats were observed. Results： The SDL was significantly prolonged,and the blood volume of right vestibular nucleus was reduced obviously,and the body balance was declined obviously in the model group,when compared to those in the sham operation group（ P〈0. 05）. The SDL was significantly shortened,the blood volume was greatly increased in the both needling groups and in the medication group after treatment,compared to those in the model group（ P〈0. 05）; the improvements were most obvious in the fast rotating-long retaining acupuncture group. However,the fast rotating-long retaining acupuncture group did not show superiority in terms of balancing test. Conclusion： Fast rotating-long retaining acupuncture can effectively improve vestibular blood supply and alleviate the symptoms of vertigo in the rats with ischemia,which has good therapeutic effect.

关 键 词：快捻久留针刺法 后循环缺血 眩晕 治疗作用 

分 类 号：R246.1[医药卫生—针灸推拿学]