新疆疏附县人群麻疹病毒抗体水平监测分析  

Analysis of measles antibody of in Shufu,Xinjiang

作　　者：周自严[1] 李晓宁[1] 谢活强 薛振香 张周斌[1] 许建雄[1] 王鸣[1] 王玉忠 王童敏 宋雪莲 罗冬梅 阿依夏穆古丽.巴吾顿 ZHOU Ziyan;LI Xiaoning;XIE Huoqiang;XUE Zhenxiang;ZHANG Zhoubin;XU Jianxiong;WANG Ming;WANG Yuzhong;WANG Tongmin;SONG Xuelian;LUO Dongmei;Ayixiarnuguli · bawudun(Guangzhou Center for Disease Control and Prevention,Guangdong 510440,China)

机构地区：[1]广州市疾病预防控制中心,广东510440 [2]广州市从化区疾病预防控制中心 [3]疏附县疾病预防控制中心

出　　处：《医学动物防制》2018年第9期851-853,共3页Journal of Medical Pest Control

基　　金：广东省省级科技计划项目(2016A020212001);广州市科技计划项目(201704020004)

摘　　要：目的了解疏附县人群麻疹抗体水平,为当地麻疹防控策略的制定提供依据。方法按照疏附县近5年麻疹发病率高低将10个街镇分为高、中、低3个层次,采用分层随机抽样方法选取无麻疹发病的人群进行问卷调查,并采集人群静脉血2~3 ml,离心后提取血清,采用酶联免疫吸附试验(ELISA)检测麻疹Ig G抗体。结果共调查目标人群945人,平均年龄为(15.30±14.06)岁,其中麻疹抗体阳性720人,阳性率为76.19%;男性麻疹抗体阳性率为75.83%(320/422)、女性为76.16%(377/495),不同性别人群麻疹抗体阳性率差异无统计学意义(χ2=0.014,P>0.05);15~25岁组麻疹抗体阳性率最高,为80.50%(194/241),7~15岁组最低,为72.57%(164/226),各年龄组麻疹抗体阳性率差异无统计学意义(χ2=4.864,P>0.05);流动人口抗体阳性率为78.57%(55/70),户籍人口抗体阳性率为75.93%(593/781),不同户籍人口抗体阳性率差异无统计学意义(χ2=0.247,P>0.05);木什镇麻疹抗体阳性率最低,为68.24%,乌帕镇最高,为82.83%,各街镇麻疹抗体阳性率差异无统计学意义(χ2=8.253,P>0.05)。结论疏附县麻疹抗体水平总体较低,应切实加强麻疹疫苗常规免疫接种,必要时针对不同目标人群采取强化免疫措施,进一步提高疏附县人群的麻疹抗体水平。Objective To understand the status of measles antibody in Shufu County of Xinjiang and to provide scientific advice for the prevention and control of measles in local areas. Methods The questionnaire was designed to investigate the influencing factors of measles antibody. According to the incidence of measles in the last five years,10 streets in the county were divided into three levels,namely,high,moderate and low. A stratified random sampling method was used to select a population without measles to conduct a questionnaire survey. 2~ 3 ml of venous blood was collected from the population and serum was extracted after centrifugation. Measles Ig G antibody was detected by enzyme-linked immunosorbent assay（ELISA）. Results A total of 945 target populations were investigated,with an average age of（15. 30±14. 06） years,of which 720 were positive for measles antibody,and the positive rate was 76. 19%;the positive rate of male measles antibody was 75. 83%（320/422） and that of females was 76. 16%（377/495）. There was no statistically significant difference in the positive rate of measles antibody among different genders（χ2= 0. 014,P〈0. 05）; the highest positive rate of measles antibody was in the 15~ 25-year-old group,being 80. 50%（194/241）,and the lowest was in the 7~ 15-year-old group,being 72. 57%（164/226）. There was no statistically significant difference in the positive rate of measles antibody among different age groups（χ2= 4. 864,P〈0. 05）; the positive rate of antibody in floating population was 78. 57%（55/70）,and the positive rate of antibody in household registration population was 75. 93%（593/781）. There was no statistically significant difference in antibody positive rate among different household registration populations（χ2= 0. 247,P〈0. 05）. The highest positive rate of measles antibody was in Mushi Town,being 68. 24% and lowest in Wupa Town,being 82. 83%. There was no statistically significant difference in the positive rate of measles antibody among diff

关 键 词：麻疹 抗体水平 监测 

分 类 号：R511.1[医药卫生—内科学]