获得性免疫缺陷综合征相关淋巴瘤的诊治进展  

Diagnosis and treatment progress of acquired immunologic deficiency syndrome-related lymphoma

作　　者：张玉林 田亚坤 郭彩萍 吴昊 Zhang Yulin;Tian Yakun;Guo Caiping;Wu Hao(Department of lnfectious Diseases,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京佑安医院感染中心,100069

出　　处：《白血病．淋巴瘤》2018年第6期376-379,共4页Journal of Leukemia & Lymphoma

基　　金：国家自然科学基金（81371399、81571178）

摘　　要：由于人类免疫缺陷病毒（HIV）感染并破坏宿主CD4^＋T淋巴细胞导致机体免疫缺陷,恶性肿瘤成为获得性免疫缺陷综合征（AIDS）最重要的并发症之一,其中淋巴瘤位于AIDS相关恶性肿瘤第1位.HIV感染者所患淋巴瘤的临床特征与非HIV感染者明显不同,针对其化学治疗要充分考虑宿主免疫状况.文章依据国际最新研究成果和国际相关指南,对该疾病临床特征及治疗方面的注意事项进行综述.Malignancy is one of the most important complications of acquired immunodeficiency syndrome （AIDS） caused by human immunodeficiency virus （HIV） infection and destruction of host CD4-positive T lymphocytes. Lymphoma ranks first in AIDS-related malignancies. The clinical features of lymphoma patients infected with HIV are different from non-HIV infected patients. The host immune condition in anti-lymphoma chemotherapy also needs to be considered. This paper reviews the clinical characteristics of AIDS-related lymphoma and the attention in anti-lymphoma therapy according to the latest international research findings and related guidelines.

关 键 词：获得性免疫缺陷综合征 淋巴瘤 艾滋病相关 诊断 

分 类 号：R512.91[医药卫生—内科学]