中西医综合干预对不同证型肺部多重耐药菌感染的防控效果  

Prevention and control effect of integrated Chinese and Western medicine in different syndromes of multidrug-resistant organisms infection

作　　者：钱华[1] 付继京 张淑彦[3] 温丽莎[4] 吴文娟 QIAN Hua;FU Ji-jing;ZHANG Shu-yan;WEN Li-sha;WU Wen-juan(Department of Out-patient,Affiliated Hospital of Hebei University of Engineering,Handan,Hebei 056002,China)

机构地区：[1]河北工程大学附属医院门诊部,河北邯郸056002 [2]河北工程大学附属医院重症监护室,河北邯郸056002 [3]河北工程大学附属医院儿科,河北邯郸056002 [4]河北工程大学附属医院核医学科,河北邯郸056002 [5]河北工程大学附属医院心外科,河北邯郸056002

出　　处：《中国临床研究》2018年第8期1113-1116,共4页Chinese Journal of Clinical Research

基　　金：河北省邯郸市科学技术局课题(1623208061-8)

摘　　要：目的探讨中西医结合干预在多重耐药菌(MDRO)肺部感染医院防控中的实践与效果。方法采用目的抽样法,以本院2015年2月至2017年10月所有肺部感染患者为研究对象,以2016年2月开始实施中西医综合防御MDRO的时间为时间节点,将入选者分为防控措施前(防控组)306例和防控措施后(综合防控组)315例。比较两组患者送检的临床标本中MDRO的检出及MDRO肺部感染情况。结果防控组MDRO的检出率高于综合防控组,差异有统计学意义(31.41%vs 24.69%,χ2=3.980,P=0.046)。防控组MDRO肺部感染发生率高于综合防控组,差异有统计学意义(9.15%vs 5.08%,χ2=3.907,P=0.048)。综合防控组住院天数短于防控组,差异有统计学意义[(8.61±0.89)d vs(9.32±1.06)d,t=9.050,P=0.000]。综合防控组病死率低于防控组(6.35%vs11.11%,χ2=4.433,P=0.035)。结论中西医结合防控MDRO感染,能有效减少MDRO肺部感染发生,提高医疗质量。Objective To investigate the prevention and control effect of integrated Chinese and Western medicine in pulmonary infection of multidrug-resistant organisms（MDRO）. Methods All the patients with pulmonary infection in Affiliated Hospital of Hebei University of Engineering from February 2015 to October 2017 were selected as study objects.Taking the time for the implementation of integrated Chinese and Western medicine MDRO as the time node,and the patients were divided into prevention and control group（n = 306,from February 2015 to January 2016） and comprehensive prevention and control group（n = 315,from February 2016 to October 2017）. The detection of MDRO in clinical samples and pulmonary infection situation of MDRO were compared between two groups. Results The MDRO detection rate in prevention and control group was significant higher than that in comprehensive prevention and control group（31. 41% vs24. 69%,χ2= 3. 980,P = 0. 046）. The incidence rate of MDRO pulmonary infection in prevention and control group was significant higher than that in comprehensive prevention and control group（9. 15% vs 5. 08%,χ2= 3. 907,P = 0. 048）.Hospitalization day in comprehensive prevention and control group was significant fewer than that in prevention and control group[（8. 61 ± 0. 89） d vs（9. 32 ± 1. 06） d,t = 9. 050,P = 0. 000]. Fatality rate in comprehensive prevention and control group was significant fewer than that in prevention and control group（6. 35% vs 11. 11%,χ2= 4. 433,P = 0. 035）.Conclusion Using integrated Chinese and Western medicine method in the prevention and control of MDRO infection could reduce the incidence of MDRO pulmonary infection effectively and improve the quality of medical care.

关 键 词：中西医结合干预 多重耐药菌 肺部感染 辨证论治 防控 

分 类 号：R563.1[医药卫生—呼吸系统]