伴骨外浆细胞瘤多发性骨髓瘤的研究进展  

Advances in multiple myeloma with extramedullary plasmacytoma

作　　者：朱婉秋[1,2] 陈文明 Zhu Wanqiu;Chen Wenming(Beijing Chao-Yang Hospital,Capital Medical Universit;Multiple Myeloma Research Beijing,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院,100020 [2]北京多发性骨髓瘤医疗研究中心

出　　处：《国际输血及血液学杂志》2018年第4期332-337,共6页International Journal of Blood Transfusion and Hematology

基　　金：国家自然科学基金（81500164）

摘　　要：骨外浆细胞瘤为多发性骨髓瘤（MM）的少见并发症。与局限于骨髓的MM相比，伴骨外浆细胞瘤MM的预后较差，并且新药联合治疗不能克服其不良预后。笔者拟就伴骨外浆细胞瘤MM的发生率、发病机制、临床表现、治疗与预后4个方面的研究进展进行介绍。Extrameduliary plasmacytoma is a rare complication of multiple myeloma （MM）. Compared with bone-restricted MM, the prognosis of MM with extramedullary plasmacytoma is poor and even novel agent contained treatment cannot overcome it. This paper reviews the advances in MM with extramedullary plasmacytoma from following four aspects, incidence, pathogenesis, clinical manifestation, treatment and prognosis.

关 键 词：多发性骨髓瘤 浆细胞瘤 发生率 治疗 预后 骨外浆细胞瘤 

分 类 号：R733.3[医药卫生—肿瘤]