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作 者:赵伟娥 梁晓燕[1] ZHAO Wei-e;LIANG Xiao-yan(Reproductive Center,the Sixth Affiliated Hospital,Sun Yat sen University,Guangzhou 510655)
机构地区:[1]中山大学附属第六医院生殖中心,广州510655
出 处:《生殖医学杂志》2018年第9期884-887,共4页Journal of Reproductive Medicine
摘 要:辅助生殖治疗过程中,传统的促排卵方案是在卵泡早期启动,这一做法符合自然周期中卵泡发育规律。但是,固定的促排卵方案限制了其灵活应用,尤其对于恶性肿瘤近期需行放射治疗或化疗的患者。有研究认为在月经周期中,存在多个卵泡募集波,提示可在不同的时期启动促排卵。本综述旨在讨论卵泡发育理论,探讨其对临床的指导意义,为灵活促排卵方案提供理论依据。The conventional ovarian stimulation protocol for assisted reproduction treatment is to initiate in the early follicular phase.This practice is consistent with the follicular development in the natural cycle.However,the fixed ovulation induction protocol limits its flexible application,especially for patients with malignant tumors that require radiation therapy or chemotherapy in the near future.Studies have shown that there are multiple follicle recruitment waves during the menstrual cycle,suggesting that ovulation induction can be initiated at different times.The objective of this paper is to review the theory of follicular development and its clinical application,and to demonstrate the practicability of flexible protocols.
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