红景天虫草复方可促进骨骼肌和大脑组织氧合作用  

Rhodiola sinensis could Promote the Oxygenation of Skeletal Muscle and Brain Tissue

作　　者：钟壮聪[1] 刘晓海[2] Zhong Zhuangcong;Liu Xiaohai(Zhongshan College of the University of Electronic Science and Technology,Zhongshan,528400;Dalian Medical University,Dalian,116044)

机构地区：[1]电子科技大学中山学院,中山528400 [2]大连医科大学,大连116044

出　　处：《基因组学与应用生物学》2018年第9期4069-4075,共7页Genomics and Applied Biology

基　　金：电子科技大学中山学院;大连医科大学共同资助

摘　　要：为了探讨补充红景天与冬虫夏草复方对短期高原训练后骨骼肌与大脑组织氧合作用影响,本研究招募22位男性田径运动员,按照最大摄氧量配对分组成安慰剂组（placebo,P）和红景天与冬虫夏草复方组（rhodiola crenulata with cordyceps sinensis,RC）。通过在受试者进行高原训练前2周开始,使其每天摄入安慰剂和红景天与冬虫夏草复方,连续补充至2周高原训练结束为止,共计补充4周,RC组每日补充量为2 000 mg。并在高原训练前和2周训练后隔天,测量受试者在海平面高度安静状态时骨骼肌与大脑组织总血红蛋白浓度、携氧血红蛋白浓度、脱氧血红蛋白浓度和氧饱和度百分比后发现,P组大脑组织总血红蛋白浓度、携氧血红蛋白浓度、脱氧血红蛋白浓度在2周高原训练后明显低于训练前;RC组能正常维持大脑组织氧气供应;且在2周高原训练后,P与RC两组安静状态骨骼肌总血红蛋白浓度、携氧血红蛋白浓度及氧饱和度百分比明显高于训练前。这说明可以通过补充红景天与冬虫夏草复方来预防高原训练后大脑组织总血红蛋白浓度、携氧血红蛋白与脱氧血红蛋白浓度下降的情况。To explore the effects of Rhodiola crenulata/Crodyceps sinensis（RC） supplementation on oxygenation levels in human skeletal muscle and brain after short-term altitude training, 22 male long-distance track and field athletes were evenly divided into Placebo（P） and RC/CS supplemented（RC） groups based on their sea-level VO2 max. The subjects received either RC（R. crenulata 1 400 mg＋C. sinensis 600 mg/d） or placebo（starch） during a4-week training program, which consisted of 2-week sea-level training and 2-week altitude training（-2 400 m）.Reduced tissue oxygenation levels（total hemoglobin, oxyhemoglobin, deox-hemoglobin and oxygen saturation percentage（%） were found in both skeletal muscle and brain tissues 1 day after altitude training. Whereas RC group better maintained oxygenation status at normal level in brain tissue following altitude training compared with the placebo group. Moreover, muscle total hemoglobin, oxyhemoglobin and oxygen saturation percentage were significantly increased in both groups after 2-week altitude training, but no significant group difference was found.Our results indicate that RC supplementation prevents the reduced hemodynamic state of brain.

关 键 词：红景天虫草复方 高原训练 氧合作用 

分 类 号：R285.6[医药卫生—中药学]