蜂胶总黄酮在心血管疾病中的应用  

Application of propolis flavone in cardiovascular disease

作　　者：孙光伟[1,2] 邢晓虹[3] 孙文瑞 崔洪涛[5] 隋欣[5] 王伟楠[5] 何天竺[5] 姜铁超 SUN Guangwei;XING Xiaohong;SUN Wenrui;CUI Hongtao;SUI Xin;WANG Weinan;HE Tianzhu;JIANG Tiechao(The First Clinical Hospital of Jilin Province Traditional Chinese Medicine Academy of Sciences,Changchun 130021,China;Jilin University,Changchun 130000,China;China-Japan Union Hospital of Jilin University,Changchun 130033,China;No.1 Hospital of Jilin University,Changchun,130000,China;Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]吉林省中医药科学院第一临床医院,长春130021 [2]吉林大学,长春130000 [3]吉林大学中日联谊医院,长春130033 [4]吉林大学第一医院,长春130000 [5]长春中医药大学,长春130117

出　　处：《吉林中医药》2018年第8期951-953,共3页Jilin Journal of Chinese Medicine

基　　金：吉林省卫生计生委;吉林省财政厅(2016Q013);吉林省中医药管理局(ZCYJ-2016-18)

摘　　要：目的总结国外对蜂胶现代药理研究进展。方法对蜂胶总黄酮抗氧化、抗炎等生物学特性及治疗活性,与其他作用于心血管疾病机理研究进行归纳探讨,总结蜂胶总黄酮作用于心血管相关疾病的国内外研究进展;并探讨中医痰饮、瘀血、经络因素在心系疾病中的病因病机,阐发有形与无形之痰都是心系疾病的重要病因。结果瘀血日久会导致心力衰竭等危重疾病的发生,经络相关疾病多以心痛为发病热点,蜂胶总黄酮能够减轻心肌缺血范围和心肌缺血的程度,且有抗炎、抗心肌缺血等功效。结论蜂胶可以在多种心系疾病中辨证应用。Objective This article summarizes the foreign modern pharmacological research progress of propolis. Methods The biological and therapeutic activities of the total flavonoids of propolis, anti-inflammatory and other biological characteristics and therapeutic activities are summarized and discussed, and the research progress on the effect of total flavonoids of propolis on cardiovascular related diseases at home and abroad is summarized. It also discusses the etiology and pathogenesis of phlegm, blood stasis and meridian factors in heart diseases, and explains that both visible and invisible phlegm are the important causes of heart diseases. Results Blood stasis for a long time will lead to heart failure and other serious diseases, meridian related diseases as the focus of heart pain, the total flavonoids of propolis can reduce the extent of myocardial ischemia and myocardial ischemia, and have antiinflammatory, anti-myocardial ischemia and other effects. Conclusion Propolis can be used in many heart diseases.

关 键 词：蜂胶总黄酮 心肌缺血 心系疾病 

分 类 号：R282.74[医药卫生—中药学]