新疆和田地区百岁老人生活状况及生化指标的分析  

Analysis of the life condition and serum biochemical indexes of centenarian in Xinjiang Hotan

作　　者：茹鲜古丽.肉孜 玛依拉.吾甫尔 程祖亨[1] 陈凤辉[2] 邱长春[3] Ruxianguli Rouzi;Mayila Wufuer;CHENG Zu-heng;CHEN Feng-hui;QIU Chang-chun(Department of Cardiology,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Chin;Nursing College,Xinjiang Medical University,Urumqi 830011,Chin;State Key Laboratory of Medical Molecular Biology,Chinese Academy of Medical Sciences,Beijing 100005,China)

机构地区：[1]新疆医科大学第一附属医院综合心脏内科,新疆维吾尔自治区乌鲁木齐市830054 [2]新疆医科大学护理学院,新疆维吾尔自治区乌鲁木齐市830011 [3]中国医学科学院基础医学研究所分子生物学国家重点实验室,北京市100005

出　　处：《实用老年医学》2018年第8期740-743,共4页Practical Geriatrics

基　　金：国家自然科学基金资助项目(31160215)

摘　　要：目的通过调查新疆和田地区百岁老人的流行病学特征及分析生化指标,进行百岁老人与低龄老人的差异性研究。方法通过整群分层抽样的方法,对长期居住在新疆和田地区的维吾尔族人群进行抽样调查,选取年龄≥100岁的自然长寿老人为百岁组,同时选择同一地区无血缘关系已自然死亡人群,年龄在60~80岁之间,作为死亡组,对2组进行问卷调查、体格检查以及抽血化验等。结果百岁组的收缩压高于死亡组(P<0.01),腰围、血尿素氮(BUN)、肌酐(Cr)、尿酸(UA)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDLC)、载脂蛋白A(Apo A)、载脂蛋白B(Apo B)水平均低于死亡组(P<0.05或P<0.01)。比较2组人群的生活状况,百岁组生活规律、心理乐观、运动、家庭和睦、家族长寿史、饮食情况、慢性病史等方面均优于死亡组,差异有统计学意义(P<0.05)。结论新疆和田地区百岁老人普遍有着良好的生活方式,长寿因素与老年人的生活方式、遗传、环境等有关,但百岁老人平均收缩压水平较高,应该早期重视早期预防,控制血压,避免心脑血管意外的发生。Objective To investigate the epidemiological characteristics of centenarians in Hotan area and to analyze the biochemical indexes. Methods By using cluster stratified sampling method,a sampling survey on Uyghur population who lived for a long life in Xinjiang＇s Hotan region was carried out.The people with an age of 100 years old or more were selected as centenarian group. At the same time,the people aged 60-80 years old who lived in the same area,had no blood relationship and had natural death were enrolled as death group. A questionnaire survey,physical examination and blood tests were conducted in both groups. Results The systolic blood pressure in centenarian group was higher than that in death group（ P〈0. 01）,and the levels of waist circumference,blood urea（ BUN）,serum creatinine（ Scr）,blood uric acid（ UA）,blood triglycerides（ TG）,serum total cholesterol（ TC）,low density lipoprotein cholesterol（ LDL-C）,apolipoprotein A（ Apo A） and apolipoprotein B（ Apo B） in centenarian group were lower than those in death group. The rule of life,psychological optimistic,exercise,family harmony, family history of longevity, diet condition, chronic disease history in centenarian group were better than those in death group（ P〈0. 05）. Conclusions The centenarians in Xinjiang＇s Hotan region have good lifestyle,and the longevity is correlated with the lifestyle,heredity and environment.

关 键 词：百岁老人 生活状况 生化指标 影响因素 

分 类 号：R339.34[医药卫生—人体生理学]