龙岩市15岁以下儿童乙肝血清学检测分析  

Analysis of hepatitis B serlosogy tasting of children under the age of 15 in Longyan city

作　　者：邱睿[1] 张敬 吴莹[1] 陈冰[1] 吴海[1] Qiu Rui;Zhang Jing;Wu Ying(The Center for Disease Control and Prevention of Longyan City,Longyan Fujian 36400)

机构地区：[1]龙岩市疾病预防控制中心,福建龙岩350802

出　　处：《基层医学论坛》2018年第29期4081-4082,共2页The Medical Forum

基　　金：福建省卫生厅青年科研课题项目(2017-2-92)

摘　　要：目的了解福建省龙岩市15岁以下儿童乙肝流行情况,为乙肝疫苗预防接种和加强免疫提供依据。方法采用分层随机抽样的方法,采集2013年—2016年龙岩市<15岁儿童血清,以ELLSA法进行乙肝血清学标志物检测。结果龙岩市2013年—2016年调查的370名儿童HBsAg总阳性率为1.08%,HBsAb总阳性率为53.51%,性别分布无统计学差异。HBsAb随年龄的增加而显著降低,3岁以后HBsAb阳性率有较大幅度的下降,7岁~14岁组抗体阳性率略有回升。结论 3岁以上儿童乙肝抗体阳性率下降,建议对3岁以上儿童进行乙肝血清学标志物检测,对无乙肝保护效果的儿童建议进行乙肝疫苗的加强免疫。Objective To understand the sero-prevalence of hepatitis B of the children under 15 years old in Longyan city,and to provide basis for improvement of hepatitis B and booster immunization. Methods Stratified sampling was used to select the children’s serum sample,who’s age under 15 in Longyan from 2013 to 2016.The five serological markers were measured by ELISA.Results HBsAg positive rate of 370 children under the age of 15 was 1.08% from 2013 to 2016.HBsAb positive rate was 53.51%.The difference of sex had no statistical significance. HBs Ab positive rates decreased with the increase of ages. HBs Ab positive rate decreased significantly after the age of 3,and then the rate was a slight recovery in the 7-14 age group. Conclusion HBsAb positive rate was decreased in the children over the age of 3.It is recommended that Hepatitis B serlosogy tasting is encouraged in the children over the age of 3,and strengthened immunization for the children who are lack of antibody protection.

关 键 词：15岁以下儿童 乙型肝炎 血清学检测 乙肝疫苗 

分 类 号：R725.1[医药卫生—儿科]