消化道肿瘤患者术后不同胃肠减压方式对胃肠功能影响的Meta分析  

A Meta analysis of the impacts of different gastrointestinal decompression methods on gastrointestinal function in patients with gastrointestinal tumors

作　　者：张伟 朱宁宁 雷婷婷[2] 徐星鑫 ZHANG Wei;ZHU Ningning;LEI Tingting;XU Xingxin(Department of nursing,Bengbu Medical College,Bengbu 233030,China;Department of Gastrointestinal surgery,the First Affiliated Hospital of Bengbu Medical college)

机构地区：[1]蚌埠医学院护理学院,安徽蚌埠233030 [2]蚌埠医学院第一附属医院胃肠外科

出　　处：《包头医学院学报》2018年第8期8-12,共5页Journal of Baotou Medical College

基　　金：蚌埠医学院研究生科研创新计划资助项目(Byycx1715)

摘　　要：目的:系统评价消化道肿瘤患者术后无负压引流与持续负压引流对胃肠功能恢复的影响。方法:检索中国知网(CNKI)、中国生物医学文献数据库(CBM)、万方全文数据库、维普中文科技期刊数据库(VIP)、百度学术、Pub Med/MEDLINE、Cochrane Library各大数据库的随机对照试验研究(randomized control trial,RCT),检索时间限制在2000年1月至2017年12月。由2名研究者采用Cochrane系统评价法独立进行文献质量评价和数据提取,比较两种胃肠减压方式对患者术后胃肠功能恢复的影响。采用Rev Man 5.3软件进行Meta分析。结果:最终纳入18篇RCT,共1 594名患者。Meta分析结果显示,无负压引流与持续负压引流两组相比差异有统计学意义的是:首次排气时间[WMD=-0.93,95%CI为(-1.10,-0.77),P<0.001];胃管留置时间[WMD=-1.34,95%CI为(-1.45,-1.24),P<0.001],无负压引流与持续负压引流两组相比差异无统计学意义的是:术后3 d胃液引流量[WMD=-2.05,95%CI为(-4.12,0.02),P=0.05]。结论:消化道肿瘤患者术后采用无负压引流的胃肠减压方式更有利于促进患者胃肠功能的恢复。Objective ： To systematically evaluate the impacts of non - vacuum sealing drainage and continuous vacuum sealing drainage on gas- trointestinal function in patients with gastrointestinal tumors. Methods：Literatures of randonfized controlled trials （RCT） were searched by retrie- ving CNKI, CBM, Wanfangdatebase, VIP, Pubmed/MEDLINE and Cochrane Library, with the retrieval time linfit from January 2000 to December 2017. Two investigators used the Cochrane system evaluation method to evaluate the quality of literature and data extraction independently, and the impacts of different gastrointestinal decompression methods on gastrointestinal function were compared. Meta analysis was performed by using Rev- Man5.3 statistical software. Results： A total of 18 RCT were recruited, which included 1 594 patients. The results of Meta analysis showed ： there were statistically significant differences in the first exhaust time [ WMD - -0.93,95 % CI, （ - 1.10, -0.77）, P 〈 0. 001[ ; the gastric tube de- tention time [WMD - - 1.34,95 % CI, （ - 1.45, - 1.24）, P 〈 0. 001 ]. The difference of the amount of gastric juices between the two groups of patients had no statistical difference on the first 3 days after the surgery [ WMD - -2.05,95 % CI, （ -4.12,0.02）, P -0.05 ]. Conclusion： The non - vacuum sealing drainage is more conducive to the recovery of gastrointestinal function in patients with gastrointestinal tumors.

关 键 词：消化道肿瘤 胃肠减压 引流 胃肠功能 META分析 

分 类 号：R269.56[医药卫生—中西医结合]