天津市疱疹性咽峡炎流行特征及其环境影响因素研究  

Characteristics of herpangina epidemic and related environmental impact factors in Tianjin

作　　者：李佳萌[1] 李琳[1] 高璐[1] 董晓春[1] 刘辉[1] LI Jia-meng;LI Lin;GAO Lu;DONG Xiao-chun;LIU Hui(Institute for Infectious Diaease Control and Prevention,Tianjin Centers for Disease Control and Prevention,Tianjin 300011,China)

机构地区：[1]天津市疾病预防控制中心传染病预防控制室,天津300011

出　　处：《环境与健康杂志》2018年第4期326-329,共4页Journal of Environment and Health

基　　金：国家科技重大专项(2017ZX10103007-002)

摘　　要：目的探讨疱疹性咽峡炎的流行特点和环境的影响,为防控措施的实施提供依据。方法于2015—2016年调查天津市504例疱疹性咽峡炎患者(1日龄~13岁)症状,对咽拭子和粪便样本进行病原学检测,调查疱疹性咽峡炎患者的卫生习惯及环境条件。结果疱疹性咽峡炎患者症状以发热为主,占全部病例的80.95%(408/504),其中,高热占70.59%(288/408);CA10阳性的病例最多,占病原阳性病例的22.78%(59/259);流行高峰为夏季,病例数是同期手足口病病例数的1.7倍;肠道病毒阳性的疱疹性咽峡炎患者其幼儿园专用毛巾的比例和幼儿园定期消毒的比例均低于肠道病毒阴性者;多因素logistic回归分析显示家庭户厕为旱厕的患者肠道病毒阳性的概率高于非旱厕家庭(OR=3.466,95%CI:1.118~10.747)。结论天津市疱疹性咽峡炎的主要病原为CA10,症状以高热为主,良好的环境卫生条件有利于降低该病的发病风险。Objective To explore the characteristics of herpangina epidemic and related environmental impact factors,and provide basis for the related prevention and control measures. Methods The data of 504 herpangina cases, aged from one day to 13 years, examined for pathogen in faeces and throat swab samples, were investigated, and the number of herpangina,enterovirus for herpangina cases and environmental and health habit factors of herpangina cases were collected and analyzed in Tianjin 2015-2016. Results Fever was the most common symptom of herpangina cases, and accounted for 80.95%（408/504）of the total cases, and revealed a proportion of 70.59%（288/408） for high fever. CA10 was the main pathogen, and revealed a detection rate of 22.78%（59/259） among cases with enterovirus infection. The number of herpangina cases increased in summer,and revealed 1.7 times as high as that of hand, foot, and mouth disease. The proportions of special towels for kindergarten and periodic disinfection in kindergarten were both lower, the proportion of family with dry latrine was higher in the herpangina cases of enterovirus infection compared with those without enterovirus infection（all P〈0.05）. The multivariate logistic regression analysis showed that prevalance of herpangina cases of enterovirus infection among total cases, whose families using dry latrines, was higher than those using water flushing latrines（OR=3.466, 95%CI： 1.118~10.747）. Conclusion Herpangina cases characterized with high fever are commonly infected by CA10 in Tianjin,good environmental sanitation contributes to reduce its epidemic.

关 键 词：疱疹性咽峡炎 环境卫生 流行特征 卫生厕所 

分 类 号：R181.3[医药卫生—流行病学]