手工血小板再回首  

Looking whole-blood derived platelets back

作　　者：李蓓 李继明 杜滨 王同显 LI Bei;LI Jiming;DU Bin

机构地区：[1]青岛市中心血站,山东青岛266071

出　　处：《临床血液学杂志（输血与检验）》2018年第4期649-652,共4页Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)

基　　金：青岛市中心血站科研计划项目(No:2017-X202)

摘　　要：目前临床输注用血小板（Platelet,PLT）制品有2种,1种是机采血小板（Apheresis platelet,AP）,另1种是从采集全血再分离出浓缩血小板（Whole-blood derived platelet,WBP）,后者的制备方法又有富血小板血浆（Platelet-rich-plasma,PRP）法和白膜（Buffy-coat,BC）法,美国多用PRP法,欧洲多用BC法,且多以4~6人份汇集（pooled）为1个治疗量[1]。Platelet products are in short supply nowadays,while preparation of whole-blood platelets（WBPs）is shrinking year by year.It was generally recognized that apheresis platelets（Aps）have been superior to WBPs in many aspects.After universal leukoreduction for whole-blood,however,not only the efficacy but also the risks of transfusion-related adverse events,including bacterial contamination,virus spreading,alloimmunization,transfusionassociated acute lung injury,are nearly the same.Hence,WBPs should be picked up in absence of new evidence.

关 键 词：手工血小板 机采血小板 疗效 输血相关不良事件 

分 类 号：R457.1[医药卫生—治疗学]