丙烯酸-甲基丙烯酸三氟乙酯嵌段共聚物的微流控自组装及模拟  

Microfluidic Self-Assembly and Simulation of Acrylic Acid and Trifluoroethyl Methacrylate Block Co-Polymer

作　　者：朱成志 冯梦然 马帅 喻聪 张超灿[1] 陈艳军[1] Chengzhi Zhu;Mengran Feng;Shuai Ma;Cong Yu;Chaocan Zhang;Yanjun Chen(School of Materials Science and Engineering,Wuhan University of Technology,Wuhan 430070,China)

机构地区：[1]武汉理工大学材料科学与工程学院,湖北武汉430070

出　　处：《高分子材料科学与工程》2018年第8期107-112,共6页Polymer Materials Science & Engineering

基　　金：国家自然科学基金资助项目(50803048);国家级大学生创新创业训练计划(20171049701014)

摘　　要：微流控是一种处理微量流体的新型技术,为纳米材料持续可控的自组装提供一个高通量平台。文中研究了丙烯酸-甲基丙烯酸三氟乙酯嵌段共聚物在同轴微流控装置中的自组装行为,利用COMSOL Multiphysics对微流控中两相液体的混合扩散进行了模拟。结合模拟分析重点探讨了外相流速和内外相总流速对共聚物胶束的粒径和形态的影响。结果表明,通过外相流速的改变可调节两相液体的混合效率进而影响共聚物自组装。随着外相流速的增加,共聚物胶束平均粒径变小,分布变宽,并从球形向其它形态开始转变。总流速的增加导致共聚物在微通道内滞留时间变短,使胶束粒径减小。Microfluidic is a novel technology of manipulating microfluid and has extensive applications in many fields,such as biological-medicine and chemistry.Its hydrodynamic flow offers a high throughput platform for the continuous and controllable self-assembly of the amphiphilic materials.In this paper,the self-assembly behavior of acrylic acid and trifluoroethyl methacrylate block copolymer（coded as PAA-b-TFEMA）in a selfdesigned coaxial microfluidic device was investigated.The mixing of two-phase streams in the microfluidic channels was simulated and analyzed by the COMSOL Multiphysics software.The results show that the mixing degree of two-phase streams is controlled by the flow rate of the outer-phase stream,which has great effects on the self-assembly behaviors of PAA-b-TFEMA.Increasing flow rate of the outer-phase stream,the average size of the self-assembled micelles decreases and the size distribution becomes wider.The morphology of micelles also transforms from sphere to other shapes.Increasing the total flow rate leads to a shorter residence time of copolymer chains in microfluidic channels,which causes decrease of the micelle size.

关 键 词：微流控 含氟嵌段共聚物 自组装 模拟 

分 类 号：TQ325.7[化学工程—合成树脂塑料工业]