门诊老年患者潜在不适当用药情况调查及影响因素分析  

Analysis of prevalence and risk factors of potentially inappropriate medication in elderly outpatients

作　　者：孙艳萍[1] 王烨[1] 邢玉晶[1] 李珍[1] 李影影[1] 蔡郁[1] SUN Yan-ping;WANG Ye;XING Yu-jing;LI Zhen;LI Ying-ying;CAI Yu(Department of Pharmacy,Beijing Geriatric Hospital,Beijing 100095,China)

机构地区：[1]北京老年医院药剂科,北京100095

出　　处：《中国新药杂志》2018年第16期1939-1944,共6页Chinese Journal of New Drugs

基　　金：北京市属医院科研培育计划项目(PX2016064)

摘　　要：目的:调查分析门诊老年患者的潜在不适当用药(PIM)情况及影响因素。方法:采用问卷调查方式,调查来我院门诊就诊的老年患者(≥60岁),以中国老年人PIM目录和中国老年人疾病状态下PIM初级判断标准为依据,对患者的PIM情况及影响因素进行分析。结果:回收有效问卷590份。患者平均年龄(70.27±8.05)岁,平均患病种数(2.90±1.57)种,平均用药品种(4.01±2.37)种。590例老年患者中,共152例(25.77%)发生了至少1项PIM,其中135例(22.89%)患者使用了中国老年人PIM目录中的药物,38例(6.44%)患者存在与疾病状态相关的PIM。Logistic回归分析显示,患者的合并用药种数和所患疾病(冠心病、糖尿病、失眠)是门诊老年患者PIM的独立风险因素。结论:依据中国老年人PIM目录和疾病状态下PIM初级判断标准,门诊老年患者PIM现状不容乐观,影响因素有患者的用药种数和所患疾病,需要医务工作者重点关注。Objective： To analyze the prevalence and risk factors of potentially inappropriate medication（ PIM） among elderly outpatients. Methods： Outpatients aged ≥60 years old were recruited into this questionnaire survey. The list of PIM for the Chinese aged people and primary standard of PIM in Chinese aged people under morbid state were used as the references to analyze the prevalence and risk factors of PIM in elderly patients.Results： The average age of 590 enrolled outpatients was（ 70. 27 ± 8. 05） years and the average number of diseases was（ 2. 90 ± 1. 57）. For each patient,（ 4. 01 ± 2. 37） kinds of medicines were being used. Among the surveyed subjects,152（ 25. 77%） had at least 1 case of PIM,135（ 22. 89%） used drugs included in the Chinese PIM List and 38（ 6. 44%） uesd PIM under morbid state. Logistic regression analysis showed that the number of combined medications and disease or disease states were independent risk factors for PIM. Conclusion： The prevalence of PIM judged according to the Chinese PIM list and primary standard of PIM under morbid state is not optimistic in elderly outpatients. Risk factors of PIM are the number of combined medications and disease or disease states.

关 键 词：老年 门诊患者 潜在不适当用药 用药分析 中国老年人PIM目录 

分 类 号：R969.3[医药卫生—药理学]