Synthesis and DNA Adsorption of Poly(2-Vinyl-4,6-Diamino-1,3,5-Triazine)Coated Polystyrene Microspheres  

作　　者：黄雷 王小涛 XIE Xun XIE Weihong LI Xuefeng GONG Xinghou LONG Shijun GUO Huiling 刘最芳 

机构地区：[1]Hubei Provincial Key Laboratory of Green Materials for Light Industry, School of Materials and Engineering, Hubei University of Technology [2]Collaborative Innovation Center of Green Light-weight Materials and Processing, Hubei University of Technology [3]School of Food and Biological Engineering, Hubei University of Technology

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2018年第4期999-1006,共8页武汉理工大学学报（材料科学英文版）

基　　金：the National Natural Science Foundation of China(Nos.51303049,51603065 and 21401051)

摘　　要：To take advantage of the polymer＇s special properties, we synthesized PVDAT coated polystyrene（PVDAT@PS） microspheres through semi-continuous precipitation polymerization, and demonstrated the possibility of controlling the size of microspheres by using different sized PS cores. Mechanism of the microsphere synthesis was investigated. Preliminary application studies indicated that the synthesized microspheres adsorbed double-stranded DNAs（dsDNAs） comprising A-T base pairs in pH7.4 phosphate buffered saline, and the adsorption capacity was in a range of 3.28 mg to 5.58 mg per gram PVDAT@PS microspheres depending on A-T base pair percentage and chain length of the dsDNAs.To take advantage of the polymer＇s special properties, we synthesized PVDAT coated polystyrene（PVDAT@PS） microspheres through semi-continuous precipitation polymerization, and demonstrated the possibility of controlling the size of microspheres by using different sized PS cores. Mechanism of the microsphere synthesis was investigated. Preliminary application studies indicated that the synthesized microspheres adsorbed double-stranded DNAs（dsDNAs） comprising A-T base pairs in pH7.4 phosphate buffered saline, and the adsorption capacity was in a range of 3.28 mg to 5.58 mg per gram PVDAT@PS microspheres depending on A-T base pair percentage and chain length of the dsDNAs.

关 键 词：2-vinyl-4 6-diamino-l 3 5-triazine PVDAT@PS DNA adsorption semi-continuousprecipitation polymerization 

分 类 号：TQ317[化学工程—高聚物工业] TQ424