原发性肝癌证型分布及用药分析  

Distribution of TCM Syndromes of Primary Liver Cancer and Drug-Use Characteristics of TCM Treatment

作　　者：钱丽丽 赵向丽[1] 冯晓军 黄雪[1] 张树辉[1] QIAN Li-li;ZHAO Xiang-li;FENG Xiao-jun;HUANG Xue;ZHANG Shu-hui(Yueyang Hospital of Integrated Traditional Chinese anti Western Medicine Affiliated to Shangha University of Traditional Chinese Medicine,Shanghai,China,20043)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437

出　　处：《河南中医》2018年第8期1189-1193,共5页Henan Traditional Chinese Medicine

基　　金：上海中医药大学中西医结合Ⅰ类高原学科项目(编号:30304114325)

摘　　要：目的:探讨原发性肝癌中医证型分布特点及中医治疗用药特点。方法:收集、整理2004年1月1日至2017年3月1日就诊于上海中医药大学附属岳阳中西医结合医院肿瘤科的原发性肝癌患者248例,进行中医辨证分型,辨证论治,采用SPSS 24.0统计软件对中医证型、中药进行频次分析。结果:248例肝癌患者中,肝郁脾虚证85例(34.3%),气滞血瘀证63例(25.4%),肝肾阴虚证54例(21.8%),湿瘀互结证31例(12.5%),湿热内蕴证15例(6.0%),肝郁脾虚证、气滞血瘀证、肝肾阴虚证出现频率最高;临床用药中,补虚药(27.2%)、利水渗湿药(14.8%)、清热药(14.1%)出现频率最高;排名前十的药物依次为白术、柴胡、陈皮、茯苓、半夏、山楂、当归、黄芪、半枝莲、山药。结论:肝郁脾虚证、气滞血瘀证、肝肾阴虚证是原发性肝癌患者的常见证型,临床治疗常用补虚药、利水渗湿药、清热药。Objective： To probe into distribution of TCM syndromes of primary liver cancer and its drug-use characteristics of TCM treatment. Methods： Two hundred and forty-eight cases of primary liver cancer treated in the oncology department of Yueyang Integrated Traditional Chinese Medicine and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine from January 1,2004 to March 1,2017,were collected. The syndrome differentiation of TCM was carried out. The frequency analysis of TCM syndrome type and Chinese medicine was analyzed by SPSS 24 software. Results： Among the 248 cases of liver cancer,there were 85 cases（ 34. 3%） of liver stagnation and spleen deficiency syndrome,63 cases of qi stagnation and blood stasis syndrome（ 25. 4%）,54 cases of deficiency of liver kidney yin（ 21. 8%）,31 cases（ 12. 5%） with damp and stasis syndrome,15 cases（ 6%） of damp heat syndrome. Liver qi stagnation and spleen deficiency syndrome,qi stagnation and blood stasis syndrome,liver kidney yin deficiency syndrome had the highest frequency rate. In clinical medication,the highest frequencies were deficiency-reinforcing medicine（ 27. 2%）,Chinese medicinal herbs for promoting dieresis and resolving dampness（ 14. 8%） and heat-clearing Chinese medicinal herbs（ 14. 1%）. The top ten drugs were Baizhu（ Rhizoma Atractylodis Macrocephalae）,Chaihu（ Radix Bupleuri）,Chenpi（ Pericarpium Citri Reticulatae）,Fuling（ Poria）,Banxia（ Rhizoma Pinelliae）,Shanzha（ Fructus Crataegi）,Danggui（ Radix Angelicae Sinensis）,Huangqi（ Radix Astragali）,Banzhilian（ Herba Scutellariae Barbatae）,Shanyao（ Rhizoma Dioscoreae）. Conclusion： Liver stagnation and spleen deficiency syndrome,qi stagnation and blood stasis syndrome,and liver kidney yin deficiency syndrome are the most commonly-seen types of primary liver carcinoma,and in clinical practice,deficiency-reinforcing medicine,Chinese medicinal herbs for promoting dieresis and resolving dampness,and heat-clearing Chinese me

关 键 词：原发性肝癌 肝郁脾虚证 气滞血瘀证 肝肾阴虚证 补虚药 利水渗湿药 清热药 

分 类 号：R273[医药卫生—中西医结合]