湖州市2011年-2016年手足口病流行病学特征和病原学监测分析  

Epidemiologic features of hand-foot-mouth disease and pathogen monitoring during 2011-2016 in Huzhou

作　　者：姚文庭[1] 朱新凤[1] 吴晓芳[1] YAO Wen-ting;ZHU Xin-feng;WU Xiao-fang(Huzhou Center for Disease Control and Prevention,Huzhou,Zhejiang 313000,China)

机构地区：[1]湖州市疾病预防控制中心,浙江湖州313000

出　　处：《中国卫生检验杂志》2018年第16期2024-2026,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解2011年-2016年湖州市手足口病病原学和流行特征,为制定预防控制措施提供科学依据。方法收集2011年-2016年湖州市手足口病疫情资料,分析流行病学和病原学特征。结果 2011年-2016年湖州市共上报手足口病患者25 672例,其中重症9例,死亡3例。发病年龄以0岁~5岁儿童为主,散居儿童居多。发病时间呈现2个高峰,分别为4月-7月和9月-12月。2 366份手足口病标本,PCR检测阳性1 684份,阳性率为71.17%。阳性标本中,EV71型阳性364份(占21.62%),Cox A16阳性474份(占28.15%),其他肠道病毒846份(占50.24%)。结论 2011年-2016年湖州市手足口病以其他肠道病毒感染流行为主,重症患者EV71占绝大多数。Objective To analyze epidemic situation of hand-foot-mouth disease（ HFMD） during 2011-2016,so as to provide scientific basis for formulating the prevention and control measures of this disease. Methods Data on HFMD outbreaks were collected from 2011 to 2016 to analyze the epidemiological and pathogenic features. Results During 2011-2016,25 672 cases of hand,foot and mouth disease were reported in Huzhou,including 9 severe cases and 3 death cases. The age of onset was mainly within 0-5 years old,with the majority in scattered children. The onset time showed two peaks,which were distributed from April to July and September to December. In the 2 366 samples of HFMD,PCR tests were positive in 1 684 cases,with the positive rate of 71. 17%. Among the positive samples,364 cases were positive for EV71（ 21. 62%）,474 cases were Cox A16（ 28. 15%）,and 846 cases were other enteroviruses（ 50. 24%）. Conclusion HFMD in Huzhou was dominated by other enterovirus infections during 2011-2016,and critically ill cases were mainly caused by EV71.

关 键 词：手足口病 肠道病毒 流行病学 病原学 

分 类 号：R512.5[医药卫生—内科学]