血液透析与腹膜透析治疗终末期糖尿病肾病的临床疗效对比研究  

Comparative study of hemodialysis and peritoneal dialysis in the treatment of end-stage diabetic nephropathy

作　　者：余效辉 何贵珍 涂强 Yu Xiaohui;He Guizhen;Tu Qiang(Nephrology Department,The Third People＇s Hospital of Jingdezhen,Jingdezhen,Jiangxi,333000 China)

机构地区：[1]景德镇市第三人民医院肾内科,江西景德镇333000

出　　处：《当代医学》2018年第25期17-19,共3页Contemporary Medicine

摘　　要：目的比较血液透析(HD)与腹膜透析(CAPD)对终末期糖尿病肾病(ESDN)的临床疗效,以探讨治疗ESDN的最佳透析治疗方法。方法选取2014年2月~2016年2月于本院诊断的ESDN患者130例,其中65例患者给予HD治疗为HD组,65例患者给予CAPD治疗为CAPD组,比较两组患者生存率、并发症及生化检验指标等情况。结果生存率:CAPD组半年生存59例,1年生存45例,生存率略高于HD组,但两组差异比较无统计学意义;并发症:CAPD组发生心脑血管事件13例,出血11例,感染14例,营养不良20例CAPD组心脑血管事件、出血事件均明显少于HD组(P<0.05),感染与营养不良比较差异比较无统计学意义;生化检验指标:CAPD组透析后收缩压(140.3±17.3)mmHg、血白蛋白(27.8±5.4)g/L,均明显低于HD组(P<0.05),其余指标比较差异无统计学意义。结论应结合患者的个体情况选择合适的透析方案,并及时的监测,必要时更换透析方案,从而提高患者的生活质量及生存率。Objective To compare the clinical effects of hemodialysis （HD） and peritoneal dialysis （CAPD） on end-stage diabetic nephropathy （ESDN） in order to explore the best dialysis treatment for ESDN. Methods 130 cases of ESDN patients diagnosed in our hospital from February 2014 to February 2016 were selected, of which 65 patients were treated with HD as HD group and 65 patients were treated with CAPD in CAPD group. The survival rate, complications and biochemical test indexes were compared in the two groups. Results Survival rate： CAPD group half year survival rate 59 cases, 1 year survival 45 cases, survival rate slightly higher than HD group, but the difference between two groups has no statis- tical significance. Complications： in group CAPD, there were 13 cases of cardiovascular and cerebrovascular events, 11 cases of hemorrhage, 14 cas- es of infection and 20 cases of malnutrition. Cardiovascular and cerebrovascular events and bleeding events were significantly less than those in group HD （P〈0.05）, and there was no significant difference between infection and malnutrition. Biochemical test index： the systolic pressure （140.3±17.3） mmHg and serum albumin （27.8±5.4） g/L after dialysis in group CAPD were significantly lower than that in group HD （P〈0.05）, and there was no significant difference between the other indexes. Conclusion The appropriate dialysis scheme should be selected according to the individual condition of the patient, timely monitoring and replacement of the dialysis plan when necessary, so as to improve the quality of life and survival rate of the patients.

关 键 词：糖尿病肾病 腹膜透析 血液透析 

分 类 号：R692.5[医药卫生—泌尿科学] R587.2[医药卫生—外科学]