强化期联合静脉给药治疗支气管结核的疗效分析  

Analysis of the Efficacy of Combined Intravenous Dosing for Bronchial Tuberculosis

作　　者：张舒[1] 龚惠莉 朱华萍 马斌 许靖[1] 范艳红[1] 付佑辉[1] ZHANG Shu;GONG Huili;ZHU Huaping(Department of Respiratory Medicine,Seventh People＇s Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai City 200137)

机构地区：[1]上海中医药大学附属第七人民医院呼吸内科,上海市200137 [2]上海市浦东新区肺科医院肺科 [3]上海市浦东新区凌桥社区卫生中心防保科 [4]上海市浦东新区高东社区卫生中心

出　　处：《医学理论与实践》2018年第17期2541-2542,2549,共3页The Journal of Medical Theory and Practice

基　　金：上海市浦东新区卫计委联合攻关项目(PW2015D-11)

摘　　要：目的:分析强化期联合静脉给药治疗支气管结核的临床疗效。方法:以2014年1月—2017年12月为病例选取时间,纳入92例支气管结核患者,按照来院就诊登记先后顺序分为对照组、研究组,各46例,分别予以常规抗结核口服治疗、强化期联合静脉给药治疗,对比效果。结果:治疗3个月、6个月、12个月后,研究组的痰菌阴转率均明显高于对照组,对比差异有统计学意义(P<0.05);研究组患者治疗1年的总有效率为95.65%,明显高于对照组的76.09%,对比差异有统计学意义(P<0.05);两组患者不良反应发生率对比差异无统计学意义(P>0.05)。结论:在常规治疗基础上,于强化期予以支气管结核患者联合静脉给药治疗,能够促进痰菌阴转,提升临床治疗总有效率,且不会增加不良反应,效果理想,安全可靠,推广应用价值高。Objective： To analyze the clinical efficacy of intensive period combined with intravenous administration for the treatment of bronchial tuberculosis. Methods ： From January 2014 to December 2017 as the time of the selected cases,92 patients with bronchial tuberculosis were included. The patients were divided into a control group and a study group according to the order of visits to the hospital,46 patients each,they were treated with routine oral anti-tuberculosis treatment or combined intravenous treatment,contrast effect. Results： After treatment for 3 months,6 months and 12 months,the sputum negative conversion rate in the study group was significantly higher than that in the control group,the difference was statistically significant（ P 〈 0. 05）. The study group patients were treated for 1 year. The total effective rate of treatment was 95. 65%,which was significantly higher than that of the control group（ 76. 09%）,the difference was statistically significant（ P 〈 0. 05）. The difference in the incidence of adverse reactions between the two groups was not significant. Statistically significant（ P 〉 0. 05）.Conclusion： On the basis of conventional therapy,bronchial tuberculosis in combination with intravenous therapy during the intensive period can promote sputum negative transformation,increase the total efficiency of clinical treatment,and will not increase adverse reactions,the effect is ideal,safe and reliable,and the value of popularization and application high.

关 键 词：强化期 静脉给药 支气管结核 

分 类 号：R521.2[医药卫生—内科学]