两种方法检测孕妇乙肝表面抗原的结果分析  

Analysis on Utcomes of Two Detection Methods Hepatitis B Surface Antigen about Pregnant Women

作　　者：汪六庆 周银娣[2] WANG Liu-qing;ZHOU Yin-di(Department of Cl inial Laboratory,The Third People＇s Hospital of Hefei 230031)

机构地区：[1]安徽省合肥市第三人民医院检验科,230031 [2]合肥市第一人民医院检验科

出　　处：《临床输血与检验》2018年第5期534-535,共2页Journal of Clinical Transfusion and Laboratory Medicine

摘　　要：目的分析酶免疫法与胶体金法检测孕妇乙肝表面抗原的结果,为临床提供参考依据。方法利用酶免疫法测定本院孕妇乙肝5项,收集乙肝表面抗原阳性血清与阴性血清共260例,其中阳性160例,阴性100例,采用胶体金法检测,对检测结果进行统计分析。结果酶免疫法与胶体金检测共有150例阳性结果相吻合,100例阴性结果完全相同,10例结果不符合,金标法阳性预测率为98.3%,特异性为100.0%,灵敏度为98.1%,准确度为98.2%,两者比较差异无统计学意义。结论金标法与酶免疫法检测相比,具有快速、简便等优点,能满足临产孕妇急诊检测的需要,可以用来筛查,但不能完全取代酶免疫法。Objective We compare the outcomes of Hepatitis B surface antigen（HbsAg）by enzymelinked immunosorbent assay with colloidal gold method in order to provide reference for clinic. Methods The five markers of Hepatitis B in pregnant women were detected by enzymelinked immunosorbent assay,there are 60 positive serum and 100 negative serum. Those samples were detected by colloidal gold method again. Results Both methods may detect 150 same positive outcomes and 100 negative outcomes,only 10 sample was discrepancy.,Positive predictive value of colloidal gold method was 98.3%,specificity was 100%,sensitivity was 98.1%,accuracy was 98.2%. Conclusions Compared to chemiluminiscence,Colloidal gold method is rapid、convenient,can satisfy the pregnatnt need,but can not replace chemiluminiscence.

关 键 词：孕妇 乙肝表面抗原 

分 类 号：R512.62[医药卫生—内科学]