六味消乳散外敷联合乳房按摩治疗乳汁淤积性乳腺炎疗效观察  

Clinical Observation on Liuwei Xiaoru Powder External Application Combined with Breast Massagein Treatment of Galactostasis Mastitis

作　　者：喻培 曾敬雅 邓小丽[1] 王丽[1] 仲丙广[1] 王秀[1] YU Pei;ZENG Jingya;DENG Xiaoli;WANG Li;ZHONG Bingguang;WANG Xiu(Dazhou Hospital of Integrative Medicine,Dazhou Sichuan China 63500)

机构地区：[1]达州市中西医结合医院,四川达州635002

出　　处：《中医学报》2018年第8期1571-1575,共5页Acta Chinese Medicine

基　　金：四川省达州市市级医学科研项目(201515)

摘　　要：目的:观察六味消乳散外敷联合乳房按摩治疗乳汁淤积性乳腺炎的临床疗效及对炎症因子的影响。方法:将98例患者随机分为对照组和观察组,每组49例。对照组采用乳房按摩治疗,观察组在对照组治疗基础上加用六味消乳散外敷治疗,每天2次。两组患者均治疗3 d。3 d后采用疼痛数字分级法(numeric rating scale,NRS)评价胀痛程度,并进行乳房肿胀硬度和气滞热壅证评分,记录每日乳汁排出量,检测治疗前后血清C-反应蛋白(C-reactive protein,CRP)、白细胞介素-6(interleukin-6,IL-6)和白细胞介素-1α(Interleukin-1α,IL-1α)水平,并对治疗前后血常规进行检查。结果:观察组临床疗效有效率为95.92%,高于对照组的79.59%,差异有统计学意义(P<0.05);观察组在治疗后第2天和第3天NRS评分低于对照组,差异有统计学意义(P<0.01);观察组在治疗后第1天、第2天和第3天,乳汁排出量均多于对照组,差异均有统计学意义(P<0.01);治疗后第2天和第3天观察组患者乳房肿胀硬度评分均低于对照组,差异均有统计学意义(P<0.01);治疗后观察组乳汁排泄、乳房胀痛、乳房结块和乳房红肿4个主症评分、次症评分和气滞热壅证积分均显著下降且低于对照组,差异均有统计学意义(P<0.01);治疗后观察组患者血清CRP、IL-6和IL-1α水平均低于对照组,差异均有统计学意义(P<0.01);治疗后观察组患者白细胞和中性粒细胞计数均低于对照组,差异均有统计学意义(P<0.01)。结论:六味消乳散外敷联合乳房按摩治疗乳汁淤积性乳腺炎能快速缓解患者疼痛、肿胀等症状,促进乳汁排出,控制感染与炎症反应。Objective： To observe the clinical efficacy of Liuwei Xiaoru Powder external application combined with breast massage in treatment of galactostasis mastitis and its influence on inflammatory factors. Methods： 98 patients were randomly divided into control group and observation group,with 49 cases in each group. The control group was treated with breast massage. The observation group was treated with external treatment of Liuwei Xiaoru Powder in addition to that of the control group twice a day. Both groups were treated for 3 days. NRS was used to evaluate the degree of pain,and breast swelling hardness and stagnation of heat stagnation were recorded. Daily milk output was recorded. Serum C-reactive protein（ CRP）,interleukin-6（ IL-6） and interleukin-1α（ IL-1α）levels was measured and blood tests were carried out before and after treatment. Results： The effective rate of clinical curative effect in the observation group was 95. 92%,which was higher than that of the control group（ 79. 59%）. The difference was statistically significant（ P〈0. 05）. The observation group had lower NRS scores than the control group on the second and third days after treatment. The difference was statistically significant（ P〈0. 01）. In the observation group on the 1 st,2 ndand 3 rddays after treatment,the milk discharge was more than that of the control group,and the difference was statistically significant（ P〈0. 01）. The breast swelling and hardness scores of the observation group in the observation group were significantly lower than that in the control group on the 2 ndand the 3 rdday（ P〈0. 01）. After treatment,the milk excretion,breast tenderness,breast agglomeration and breast redness were observed in the 4 main groups. The scores of disease,sub-disasters,and stagnation of heat-stagnation syndromes all decreased significantly and were significantly lower than those in the control group（ P〈0. 01）. The levels of serum CRP,IL-6,and IL-1α in the observation group after treatment were

关 键 词：乳汁淤积性乳腺炎 六味消乳散 按摩 中医药疗法 中西医结合 

分 类 号：R271.44[医药卫生—中医妇科学]