肿瘤相关性贫血的患病情况及与性别、年龄和肿瘤类型的相关性分析  

Prevalence of cancer related anemia and its relationship with gender,age and tumor types

作　　者：李石[1] 宋晓玉[1] 张莉[1] LI Shi;SONG Xiaoyu;ZHANG Li(Department of Clinical Laboratory,Sichuan Cancer Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]四川省肿瘤医院检验科,成都610041

出　　处：《检验医学与临床》2018年第18期2722-2724,2728,共4页Laboratory Medicine and Clinic

摘　　要：目的了解肿瘤相关性贫血(CRA)的患病情况,并分析其与性别、年龄和肿瘤类型的相关关系。方法收集2017年1-12月该院接受检查的29 496例初治恶性肿瘤住院患者的相关实验室检查资料,计算恶性CRA的患病率,分析贫血的患病率及贫血严重程度与性别、年龄和肿瘤类型的相关关系。结果 CRA总体患病率为37.2%(10 975/29 496),轻度贫血、中度贫血、重度贫血和极重度贫血的患病率分别为18.3%、12.6%、5.5%和0.7%。不同发病部位恶性肿瘤患者的贫血患病率不同,消化系统恶性肿瘤患病率最高(61.9%),妇科恶性肿瘤次之(44.4%)。10 975例CRA患者中,轻度、中度、重度和极重度贫血患者分别占49.3%、34.0%、14.8%和2.0%。发生重度和极重度贫血主要集中在消化系统恶性肿瘤患者当中。男性CRA的患病率明显高于女性(40.5%vs.33.6%;χ2=152.041,P<0.05);随着年龄的增长,男性和女性CRA的患病率均呈明显上升趋势(均P<0.05)。<40岁、≥40~60岁和≥60岁3个年龄组患病率分别为29.7%、35.5%和43.0%,≥40~60岁和≥60岁两个年龄段男性恶性肿瘤患者的CRA的患病率均明显高于女性(P<0.05)。结论 CRA的患病率较高,消化系统恶性肿瘤最易伴发贫血,以轻度、中度贫血为主。Objective To investigate the Prevalence of cancer related anemia,and analyze the relationship between sex,age and tumor types.Methods Laboratory data of 29 496 hospitalized malignant tumors who were examined in Sichuan Cancer Hospital from January 2017 to December 2017 were collected,the incidence of cancer related anemia（CRA）were calculated,and the relationships between sex,age and tumor types were analyzed.Results The overall prevalence of cancer-related anemia was 37.2%（10 975/29 496）.The prevalences of mild anemia,moderate anemia,severe anemia and severe anemia were 18.3%,12.6%,5.5% and0.7%,respectively.The prevalence of anemia in patients with malignant tumor at different sites varies,with the highest incidence of digestive system malignancies（61.9%）and the second（44.4%）of gynecological malignancies.Among 10975 patients with anemia related to anemia,49.3%,34.0%,14.8%and 2.0% of patients with mild,moderate,severe and severe anemia respectively.The occurrence of severe and very severe anemia were mainly concentrated in patients with digestive system cancer.The prevalence of cancer-associated anemia in men was significantly higher than that in women（40.5%vs.33.6%;χ2=152.041,P〈0.05）.The prevalence of cancer-associated anemia in both men and women was significantly higher with age rising trend（all P〈0.05）.The prevalence of the three age groups40 years old,≥40-60 years old and≥60 years old were29.7%,35.5% and 43.0%,respectively.The tumor-relatedness of male malignant tumor patients aged≥40-60 years and≥60 years.The prevalence of anemia was significantly higher than that of women（all P〈0.05）.Conclusion The prevalence of cancer-related anemia is higher,with the most common malignant digestive system associated with anemia,with mild to moderate anemia.

关 键 词：肿瘤相关性贫血 血常规 横断面研究 

分 类 号：R446.111[医药卫生—诊断学]