活血化痰通络法辨治老年类风湿关节炎及对患者CRP、ESR的影响研究  

Study on the effect of activating blood and resolving Phlegm and dredge collaterals on CRP and ESR in elderly-onset rheumatoid arthritis

作　　者：李树岗[1] Li Shugang(Department of Rheumatology,the First Hospital of Wuhan,Wuhan 43000)

机构地区：[1]武汉市第一医院风湿免疫科,武汉430000

出　　处：《陕西中医》2018年第10期1429-1431,共3页Shaanxi Journal of Traditional Chinese Medicine

摘　　要：目的:通过检测老年类风湿关节炎(EORA)患者在运用活血化痰通络法治疗前后的CRP及ESR指标变化,研究活血化痰通络法辨治老年类风湿性关节炎对CRP及ESR的影响。方法:选取老年类风湿性关节炎患者共317例。随机分为治疗组159例、对照组158例,患者年龄均在60岁以上,对照组仅进行西药治疗,治疗组是在对照组西药治疗的基础上加之活血化痰通络法的中药治疗,对两组患者治疗前后进行指标检测,应用统计学方法对实验结果进行对比分析。结果:活血化痰通络法治疗组有效率为86.79%,对照组有效率为59.49%,两组对比差异有统计学意义(P<0.05);治疗组及对照组治疗前后组内的CRP及ESR的情况对比,两组组内差异均有统计学意义(P均<0.05);活血化痰通络法治疗组的CRP及ESR的改善作用高于对照组,两组对比差异均有统计学意义(P均<0.05)。结论:活血化痰通络法对老年类风湿关节炎患者有较高的治疗作用,能有效改善CRP(C-反应蛋白)及ESR(血沉)等指标,明显改善老年类风湿性关节炎患者的生活状况,可以为以后的临床应用给出真实有效的理论依据的支撑数据,对临床患者的治疗有重要的意义。Objective：To investigate the changes of CRP and ESR in elderly patients with rheumatoid arthritis （EORA） before and after treatment with activating blood and resolving Phlegm and dredge collaterals method. CRP and ESR. Methods：A total of 317 elderly patients with rheumatoid arthritis were eligible for inclusion criteria. 317 patients were randomly divided into treatment group （ n = 159） and control group （ n = 158）. The age of the patients was over 60 years old. The control group was treated only by western medicine in the control group. Of traditional Chinese medicine treatment,the two groups of patients before and after treatment of indicators,the application of statistical methods to compare the experimental results. Results：The effective rate was 86.79% in the treatment group and 59.49% in the control group. The difference between the two groups was statistically significant （ P 〈0.05）; Treatment group and control group before and after treatment group within the CRP and ESR contrast,inside two way difference had statistical significance （ P 〈 0.05） ;The improvement rate of ESR and ESR was higher than that of the control group （ P 〈0.05）. Conclusion：activating blood and resolving Phlegm and dredge collaterals method has a high therapeutic effect on elderly-onset rheumatoid arthritis,and can effectively improve the indexes of CRP and ESR,and improve the patients with rheumatoid arthritis of the living conditions can be given for future clinical application of real and effective data support for clinical treatment of patients has important significance.

关 键 词：关节炎 风湿性/中西医结合疗法 活血祛瘀剂/治疗疗法 祛痰剂/治疗应用 老年 

分 类 号：R593.22[医药卫生—内科学]