孕期PM2.5暴露对出生后个体的后期发育的影响研究进展(综述)  

Research progress on the influence of PM2.5 exposure during pregnancy on the later development of individuals after birth

作　　者：徐艳[1,2] 江德裕[1] 丁维俊 XU Yan;JIANG De-yu;DING Wei-jun(Chengdu university of traditional Chinese medicine,Ghendu 611137,Sichuan;Chengdu Medical College,Chendu 610000,Sichuan)

机构地区：[1]成都中医药大学,四川成都611137 [2]成都医学院,四川成都610000

出　　处：《安徽卫生职业技术学院学报》2018年第4期148-150,共3页Journal of Anhui Health Vocational & Technical College

基　　金：教育部博士点基金支持(编号:20135132110011)

摘　　要：胚胎期对环境压力的变化是高度敏感的,怀孕期间高暴露于周围的空气污染,空气细颗粒物(PM2.5)可通过呼吸系统进入孕妇体内,并随血液循环而影响胚胎的发育。这种由于环境压力造成的胚胎表观遗传的改变不但对胚胎发育产生毒副作用,而且对出后新生儿的成长发育也会产生潜在危险。过去焦点多集中在PM2.5对胚胎发育的不良影响,而对出生后的个体后期发育影响关注较少。该文就这一问题做一综述。Embryo stage is highly sensitive to the change of environmental pressure, high exposure to ambient air pollution during pregnancy, air fine particulate matter（PM2.5） can be introduced into a pregnant woman＇s body by the respiratory system, and affect the growth of embryo with blood circulation. Such changes in epigenetics caused by environmental stress not only have toxic and adverse effects on embryonic development, but also have potential risks to the growth and development of newborn babies after birth. In the past, the focus was mostly on the adverse effects of PM2.5 on embryonic development, but less on the later development of individuals after birth. This paper makes a summary of this problem.

关 键 词：PM2.5 产前暴露 生长发育 健康 

分 类 号：R12[医药卫生—环境卫生学]