10例心脏死亡婴幼儿肾脏捐供成人肾移植的回顾性分析  

Retrospective analysis on 10 adult kidney transplantation from children donation after cardiac death

作　　者：孙荣凯[1] 王昆[2] 郝俊文[1] 程琳 王月山 付茂辉 常征[1] 张爱民[1] SUN Rong-kai;WANG Kun;HAO Jun-wen(Dept.of Urological Surgery,Jinan Military General Hospital（former）,Jinan,Shandong 250031,China)

机构地区：[1]济南军区总医院泌尿外科,山东济南250031 [2]济南市妇幼保健院,山东济南250000 [3]山东省立第三医院,山东济南250000

出　　处：《实用医药杂志》2018年第8期699-703,共5页Practical Journal of Medicine & Pharmacy

摘　　要：目的总结婴幼儿心脏死亡肾脏捐献(DCD)供成人肾移植的临床经验,探讨其临床疗效及安全性。方法回顾性分析原济南军区总医院2012年8月—2017年1月10例婴幼儿DCD供肾成人肾移植的临床资料,总结婴幼儿心脏死亡肾脏捐献供成人肾移植的手术方法、免疫抑制剂应用、并发症及其相关处理和随访情况。结果10例成人尿毒症患者接受了婴幼儿DCD供肾移植。随访时间为(8.3±7.4)个月,肾小球滤过率评估值均逐渐增加至稳定水平,均获得了较好的生活状态。结论婴幼儿DCD供肾成人肾移植取得了较为满意的临床疗效和安全性。发育成熟的婴幼儿即可成为DCD供肾成人肾移植的合格肾源,并有望成为DCD供肾成人肾移植的重要来源。Objective To summarize clinical experience of adult kidney transplantation from children donation after cardiac death（DCD） and to discuss the clinical efficacy and safety. Methods Retrospective analysing the clinical data of 10 patients in Jinan Military General Hospital from August 2012 to January 2017,who received adult kidney transplantation from child DCD. The surgical options,immunosuppression,complications with its related treatment and follow-up were summarized. Results Ten adult renal transplantation were performed from children DCD and followed up of 8.3 ±7.4 months,estimated glomerular filtration rate（e GFR） increased to stable level. All the recipients obtained the ideal state of life respectively. Conclusions Adult kidney transplantation from children DCD is effective and safe. It is different from adult donation in organ harvesting,recipient selection,kidney trimming,surgical option and treatment after operation.

关 键 词：婴幼儿供者 肾移植 心脏死亡器官捐献 肾功能 

分 类 号：R699.2[医药卫生—泌尿科学]