虫草类药材中多球壳菌素含量的测定研究  

Determination of ISP-1 in Cordyceps

作　　者：王艺璇[1] 曹秀君 万德光[1,2] 国锦琳 Wang Yixuan;Cao Xiujun;Wan Deguang;Guo Jinlin(Key Laboratory of Standardization of Chinese Herbal Medicine of Ministry of Education Chengdu University of Traditional Chinese Medicine,Chengdu,611137,China;Research and development of traditional Chinese medicine resources system utilization,Ministry of State Key Laboratory Breeding Base,Chengdu,611137,China)

机构地区：[1]成都中医药大学中药材标准化教育部重点实验室,四川成都611137 [2]中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都611137

出　　处：《成都中医药大学学报》2018年第3期6-8,共3页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家自然科学基金(81373920);四川省中医药管理局川产道地药材综合开发与区域发展项目(2016ZY003);成都市科技惠民项目(2015-HM01-00205-SF)

摘　　要：目的:本研究旨在筛选出我国常见虫草中ISP-1含量高的种类,为下一步生产ISP-1提供优质菌种。方法:首次系统地使用HPLC对冬虫夏草、凉山虫草、蛹虫草、古尼虫草和亚香棒虫草中的ISP-1含量进行测定。结果:发现五种虫草中都含有ISP-1,蛹虫草中含量高达0. 7933 mg/g,远高于冬虫夏草。结论:从测定结果来看,蛹虫草、凉山虫草、亚香棒虫草中ISP-1含量高于冬虫夏草。可以为下一步生产ISP-1选择优质菌种提供基础。Objective： Screening varieties with high ISP-1 will to provide premium varieties for the future production. Methods： In this study, the content of ISP-1 in Ophiocordyceps sinensis, Cordyceps /iangshanensis, Cordyceps mi/itaris, Cordyceps gunnii and Cordyceps hawkesii was deter^nined by HPLC systematically for the first time. Results： Our group found that there is ISP-1 in all five cordyceps and the content as high as 0. 7933 mg/g in Cordyceps militaris,which is higher than Ophiocordyceps sinensis. Conclusion： From the measurement results, the content of ISP-1 in Cordyceps Mi/itaris, Liangshan Cordyceps, Cordyceps hawkesii is much higher than Cordyceps sinensis. It will provide the basis for selecting high-quality strains to produce ISP-1 in the future.

关 键 词：虫草 多球壳菌素 含量测定 

分 类 号：R284.1[医药卫生—中药学] R282.1[医药卫生—中医学]