实时剪切波弹性成像技术对男性不育患者睾丸硬度的检测及评估  

Detection and evaluation of testicular hardness in male infertility patients by real-time shear wave elastography

作　　者：张天义[1] 徐璇 宋兵[1] 袁国珍[1] 侯曼曼 王少春[1] 何敬海[1] 李井平 ZHANG Tianyi;XU Xuan;SONG Bing;YUAN Guozhen;HOU Manman;WANG Shaochun;HE Jinghai;LI Jingping(Department of Ultrasound,Affiliated Hostital of Ji＇ning Medical College,Shandong 272029,China)

机构地区：[1]济宁医学院附属医院超声科,山东省济宁市272029

出　　处：《临床超声医学杂志》2018年第9期614-617,共4页Journal of Clinical Ultrasound in Medicine

基　　金：山东省医药卫生科技发展计划项目(2013WS0341)

摘　　要：目的应用实时剪切波弹性成像(SWE)技术测量睾丸硬度,探讨该项技术在男性少弱精症患者中的临床应用价值。方法选取我院诊断为少弱精症患者118例,其中轻度少弱精症组33例,中度少弱精症组35例,重度少弱精症组50例;另选睾丸正常且无泌尿系疾病的健康志愿者500例(对照组)。应用SWE技术测量各组睾丸弹性模量值,并对其进行比较;ROC曲线分析其诊断价值。结果轻、中度少弱精症组睾丸弹性模量最大值、平均值、最小值与对照组比较,差异均无统计学意义;重度少弱精症组弹性模量最大值和平均值与对照组比较,差异均有统计学意义(均P<0.05);且当睾丸弹性模量值最大值为4.25 k Pa时,受试者工作特征曲线下面积最大(0.88),其诊断重度少弱精症患者的敏感性和特异性分别为79.4%、76.0%。结论 SWE技术可以准确地评价睾丸组织的硬度及均匀程度,为临床诊断少弱精症患者提供依据。Objective To explore the clinical application of real-time shear wave elastography（SWE） in the measurement of testicular hardness in male patients with oligospermia.Methods One hundred and eighteen patients with oligospermia were enrolled in this study.Five hundred healthy volunteers with normal testis and without urinary diseases were selected.The oligozoospermia patients were divided into three groups：33 cases of mild oligozoospermia,35 cases of moderate oligozoospermia,50 cases of severe oligospermia.All the people were measured with SWE technology and the values of elastic modulus of each group were compared.Results There was no significant difference of elastic modulus（maximum value,mean value,minimum value）between the patients with mild and moderate oligospermia and the healthy volunteers.There was significant difference of maximum and mean values of the elastic modulus values of the patients with severe oligospermia and the healthy volunteers（all P〈0.05）.When testicular elastic modulus maximum value was 4.25 k Pa,the area under the ROC curve was 0.88,the sensitivity and specificity were 79.4%,76.0%.Conclusion SWE technique can accurately evaluate the hardness and uniformity of testicular tissue,and provides the basis for the clinical study of oligospermia patients.

关 键 词：剪切波弹性成像 实时 男性不育 弹性模量 睾丸 

分 类 号：R697.22[医药卫生—泌尿科学] R445.1[医药卫生—外科学]