浅析Fite染色在麻风病诊断中的价值  

Preliminary analysis of the value of Fite staining in the diagnosis of leprosy

作　　者：施为[1] 陈明亮[1] 李芳芳[1] 鲁丽霞[1] 李吉[1] 谢红付[1] Shi Wei;ChenMingliang;Li Fangfang;Lu Lixia;Li Ji;Xie Hongfu(Department of Dermatology,Xiangya Hospital,Central South University,Changsha 410008,China)

机构地区：[1]中南大学湘雅医院皮肤科,长沙410008

出　　处：《中华皮肤科杂志》2018年第9期662-664,共3页Chinese Journal of Dermatology

摘　　要：目的评估Fite染色在麻风病组织病理中的诊断价值。方法将我科2013--2017年诊断的13例麻风及疑似麻风患者（临床及HE染色高度怀疑为麻风而抗酸染色阴性）组织病理学切片重新行Fite染色，并与抗酸染色结果对比，评估Fite染色在麻风诊断中的价值。结果6例抗酸染色阳性患者Fite染色亦为阳性；7例抗酸染色阴性的疑似麻风患者，6例Fite染色发现数量不一的麻风分枝杆菌，1例阴性。结论Fite染色可以提高麻风分枝杆菌的阳性检测率。Objective To evaluate the diagnostic value of Fite staining in leprosy histopathology. Methods Between 2013 and 2017, 13 patients diagnosed with leprosy or suspected leprosy （high suspicion of leprosy based on clinical manifestations and hematoxylin-eosin staining, but negative acid-fast staining） in our department, were enrolled into this study. The histopathological sections were subjected to Fite staining, and the results were compared with those of acid-fast staining, so as to assess the value of Fite staining in the diagnosis of leprosy. Results Six patients with positive acid- fast staining still showed positive Fite staining. Among 7 patients with suspected leprosy and negative acid-fast staining, 6 patients showed positive Fite staining with varying numbers of Mycobacterium leprae, and 1 showed negative Fite staining. Conclusion Fite staining can increase the detection rate of Mycobacterium leprae.

关 键 词：麻风 组织细胞化学 Ziehl—Neelsen染色 Fite染色 

分 类 号：R755[医药卫生—皮肤病学与性病学]