基于Design-Expert软件对原子吸收光谱仪工作参数优化  

Design and Parameter Optimization of Atomic Absorption Spectrometer Using Design-Expert Software

作　　者：廖伟 谢亨旺 刘永林[2] 才硕 苏甜 LIAO Wei;XIE Heng-wang;LIU Yong-lin;CAI Shuo;SU Tian(Irrigation Experiment Station of Jiangxi,Nanchang 330201,China;Jiangxi Institute of Analysis,Nanchang 330029,China)

机构地区：[1]江西省灌溉试验中心站,江西南昌330201 [2]江西省分析测试研究所,江西南昌330029

出　　处：《分析测试技术与仪器》2018年第3期143-150,共8页Analysis and Testing Technology and Instruments

基　　金：江西省水利厅重大水利科技资助项目(KT201502);江西省重点研发计划资助项目(20171BBH80018)

摘　　要：将响应表面试验设计方法(RSM)应用于原子吸收光谱仪工作参数优化,以铜元素为目标化合物,结合Design-Expert软件进行数据处理.结果表明,单因素试验最佳工作条件:仪器灯电流15 m A,仪器吸喷速率7 m L/min,仪器乙炔气流量3.00 L/min.中心组合试验结果表明:当吸喷速率为7 m L/min、乙炔气流量为2.25 L/min、灯电流为10 m A时,仪器灵敏度最好.In most conventional studies, design and parameter optimization of atomic absorption spectrometer（AAS） is usually carried out using a single-varialble-at-a-time （SVAT, the most common practice holding all other variable constants） method, but the method is time-consuming, cannot identify the interactions between different variables, and is inefficient to predict the true optimized parameters of the operating conditions. The central composite design（CCD） is one of the methods based on the response surface methodology（RSM）. CCD used in this study can overcome the above mentioned shortcomings. Copper is used as the target compound for the test, and the Cu concentrations were analyzed by AAS with different operating parameters of such as acetylene flow, lamp current and sample inject rate. The results showed, that the optimized conditions were acetylene flow at 3.00 L/min, lamp current at 10 mA or sample inject at 7 mL/min by the single-varialble-at-a-time. Three experimental variables including acetylene flow, lamp current and sample inject were selected in the multivariable experimental design. The optimized conditions were：acetylene flow at 2.25 L/min, lamp current at 10 mA and sample inject 7 mL/min.

关 键 词：Design-Expert 原子吸收光谱仪 响应曲面设计法 参数优化 

分 类 号：O657.3[理学—分析化学]