蛇咬伤患者抗生素不良反应的回顾性分析  

Retrospective Analysis of Adverse Drug Reactions in Patients with Snakebite

作　　者：麦超[1] 尹钰[1] 刘显群[1] 黄小琴[1] MAI Chao;YIN Yu;LIU Xian-qun;HUANG Xiao-qin(Department of Emergency,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichua)

机构地区：[1]川北医学院附属医院急诊科

出　　处：《世界最新医学信息文摘》2018年第22期101-102,共2页World Latest Medicine Information Electronic Version

基　　金：川北医学院附属医院项目资助;项目编号:2015-39

摘　　要：目的对蛇咬伤病人使用抗生素的药物不良反应进行回顾性分析,为蛇咬伤患者规范使用抗生素提供依据。方法对2017年1月1日至2017年12月30日在本院急诊科留观或住院的119蛇咬伤病人,使用抗生素的患者涉及的抗生素使用情况,发生不良反应时间、临床表现、预后等进行分析。结果 119例患者应用抗生素,其中发生不良反应的药物均为左氧氟沙星,共发生不良反应7例,其中导致中枢神经系统不良反应1例。结论对于蛇咬伤患者使用抗生素时发生药物不良反应,及时发现,正确处置,规范使用抗生素是提高蛇咬伤救治成功率的关键。Objective To review the adverse drug reactions of snakebite patients using antibiotics, and to provide the basis for the standardized use of antibiotics for snakebite patients. Methods The use of antibiotics in patients with 119 snakebite who were observed or hospitalized in the emergency department of our hospital from January 1, 2017 to December 30, 2017 had adverse reaction time, clinical manifestations, and prognosis were analysed. Results The antibiotics were used in 119 patients, and all the adverse drug reactions were levofloxacin,there were 7 cases of adverse reactions,there was 1 case of ADR in the central nervous system. Conclusion For patients with snakebite, the occurrence of adverse reactions, timely detection, correct disposal and standardized use of antibiotics are the key to improve the success rate of snakebite treatment.

关 键 词：蛇咬伤 抗生素 使用情况 不良反应 

分 类 号：R978.1[医药卫生—药品]