人迎穴改良针刺提插法对椎动脉型颈椎病患者血浆NPY及UⅡ浓度的影响  

Effects of modified needling lifting-thrusting method on Renying(ST9) on plasma concentration of NPY and UⅡ of patients with vertebral artery type of cervical spondylosis

作　　者：王艳富[1] 马朝阳[1] WANG Yan-fu;MA Chao-yang(Rehabilitation Department,Wuhan Central Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China)

机构地区：[1]华中科技大学同济医学院附属武汉中心医院康复科,武汉430014

出　　处：《中华中医药杂志》2018年第9期4231-4234,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：湖北省卫生和计划生育委员会科研项目(No.2013Z-Y29)~~

摘　　要：目的:观察人迎穴改良针刺提插法对椎动脉型颈椎病(CSA)的临床疗效,以及对患者血浆神经肽Y(NPY)、尾加压素Ⅱ(UⅡ)的浓度影响,从而探讨人迎穴改良针刺法治疗CSA的可能机制。方法:80例患者随机分为两组:观察组(人迎穴改良针刺提插法)、对照组(人迎穴常规针刺提插法),各40例。每天治疗1次,6d为1个疗程,间隔休息1d,连续治疗2个疗程。治疗结束后比较两组临床疗效以及血浆NPY、UⅡ浓度和椎动脉(LVA、RVA)、基底动脉(BA)收缩期峰值血流速度(Vs)的变化情况。结果:治疗后,观察组临床治愈效果优于对照组(P<0.01);两组颈性眩晕症状与功能评估量表(ESCV)评分治疗后均明显增加(P<0.01),且观察组ESCV评分增加程度及改善指数均高于对照组(P<0.01);两组LVA、RVA、BA的Vs均明显提高(P<0.01),且观察组较对照组效果更明显(P<0.01);两组血浆NPY、UⅡ浓度均显著下降(P<0.01),且观察组低于对照组(P<0.01)。结论:人迎穴改良针刺提插法可有效调节椎基底动脉供血,改善大脑循环,能明显提高临床疗效,为防治CSA提供了一个简便有效、切实可行的方案和理论支持,值得临床推广应用。Objective： To observe the clinical effect of modified needling lifting-thrusting method on Renying（ST9） on cervical spondylosis of vertebral artery type（CSA）, and the influence on plasma concentration of neuropeptide Y（NPY） and tail vasopressin Ⅱ（UⅡ） in the patients, so as to explore the possible mechanism of modified needling lifting-thrusting method on Renying（ST9） in the treatment of CSA. Methods： Eighty patients were randomly divided into two groups, with 40 cases in each group, which were the observation group [modified needling lifting-thrusting method on Renying（ST9）] and the control group [routine needling lifting-thrusting method on Renying（ST9）]. Treatment was conducted once a day, and continuous treatment for six days was one course of treatment. The patients could rest at intervals of one day, then were taken continuous treatment for two courses. The clinical efficacy, the plasma concentration of NPY and UⅡ, and the peak systolic blood flow（Vs） of the vertebral artery（LVA, RVA） and the basilar artery（BA） between the two groups after treatment, were compared. Results： The clinical efficacy of the observation group was better than the control group after treatment（P〈0.01）. The scores of symptoms and function of cervical vertigo（ESCV） were both significantly increased in two groups after treatment（P〈0.01）, and the increased degree of the ESCV score and the improvement index in the observation group were higher than those in the control group（P〈0.01）. The Vs of LVA, RVA and BA in two groups were all increased significantly after treatment（P〈0.01）, and the increased degree of observation group was more obvious than that of the control group（P〈0.01）. The plasma concentrations of NPY and UⅡ both decreased significantly in two groups after treatment（P〈0.01）, and there was a significant difference between the two groups（P〈0.01）. Conclusion： Modified needling lifting-thrusting method on Renying（ST9） can eff

关 键 词：人迎穴 改良针刺 椎动脉型颈椎病 神经肽Y 尾加压素Ⅱ 

分 类 号：R246.9[医药卫生—针灸推拿学]