“首辨阴阳,再辨六经”论治惠州地区2型糖尿病的临床观察  

Clinical observation of type 2 diabetes in Huizhou area based on 'the first of syndrome differentiation is yin and yang, then is the six meridians'

作　　者：谭宏韬[1] 刘树林[2] 朱章志[2] 林明欣 TAN Hong-tao;LIU Shu-lin;ZHU Zhang-zhi;LIN Ming-xin(Huizhou Hospital of Traditional Chinese Medicine,Huizhou 516000,China;No.1 Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]惠州市中医医院,广东惠州516000 [2]广州中医药大学第一附属医院,广州510405 [3]中国中医科学院中医基础理论研究所,北京100700

出　　处：《中华中医药杂志》2018年第9期4240-4244,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：2014年广东省中医药强省建设专项资金项目

摘　　要：目的:探讨立足"首辨阴阳,再辨六经"论治惠州地区2型糖尿病的临床疗效。方法:选取惠州地区2型糖尿病患者120例,随机分为对照组、观察组,对照组采取常规治疗,观察组在对照组治疗的基础上立足"首辨阴阳,再辨六经"论治,检测两组治疗前后空腹血糖(FPG)、餐后2h血糖(G-2h)、糖化血红蛋白(Hb A1c)、空腹胰岛素(FINS)、胰岛素敏感性指数(IAI)、简明健康调查表(SF-36)、2型糖尿病患者生活质量评定量表(DMQLS)及中医症候评分。结果:治疗后,对照组FPG、G-2h、Hb A1c较治疗前显著改善(P<0.05),观察组FPG、G-2h、Hb A1c、FINS、IAI、SF-36评分、DMQLS评分较治疗前亦显著改善(P<0.05);同时,观察组FINS、IAI、SF-36评分、DMQLS评分、中医临床疗效均显著优于对照组(P<0.05,P<0.01)。结论:立足"首辨阴阳,再辨六经"论治惠州地区2型糖尿病,有效控制血糖的同时可修复胰岛β细胞功能,提高胰岛素敏感性,改善临床症状及生活质量,值得在该地区进一步推广应用和深入研究。To explore the clinical efficacy of ＇the first of syndrome differentiation is yin and yang, then is the six meridians＇ to treat type 2 diabetes in Huizhou. Methods： A total of 120 patients with type 2 diabetes in Huizhou were randomly divided into the control group, the observation group. The control group was treated routinely. The observation group was treated according to the principle of ＇the first of syndrome differentiation is yin and yang, then is the six meridians＇, based on the treatment of the control group. Fasting blood glucose（FPG）, postprandial 2 h blood glucose（G-2 h）, glycosylated hemoglobin（Hb A1 c）, fasting insulin（FINS）, insulin sensitivity index（IAI）, and the Short Form（SF-36）, development and evaluation of quality of life scale（DMQLS） and TCM symptom scores were observed before and after treatment. Results： After treatment, FPG, G-2 h and Hb A1 c in the control group were significantly improved compared with those before treatment（P〈0.05）. The FPG, G-2 h, HbA1c, FINS, IAI, SF-36 and DMQLS scores in the observation group were also significantly improved compared with those before treatment（P〈0.05）; in the meanwhile, the FINS, IAI, SF-36 score, DMQLS score, and TCM symptom improvement in the observation group were better than the control group（P〈0.05, P〈0.01）. Conclusion： Based on the ＇the first of syndrome differentiation is yin and yang, then is the six meridians＇ to treat type 2 diabetes in Huizhou, blood glucose can be effectively controlled while repairing islet β-cell function, and insulin sensitivity, clinical symptoms and quality of life can also be improved. It is worth further promoting, application and in-depth research in this region.

关 键 词：阴阳 六经辨证 惠州 2型糖尿病 临床观察 胰岛素敏感性 

分 类 号：R259[医药卫生—中西医结合]