广州地区吸毒戒毒人群梅毒感染率及危险因素分析  

Prevalence and risk factors of syphilis infection among drug abusers in Guangzhou

作　　者：戴向农[1] 何婉苹[2] 汤少开[2] 庄锦填 梁容娇 叶兴东[1] DAI Xiang-nong;HE Wan-ping;TANG Shao-kai;ZHUANG Jin-tian;LIANG Rong-jiao;YE Xing-dong(Department of Dermatology;Department of Health Section,Guangzhou Institute of Dermatol-ogy,Guangzhou 510095,China)

机构地区：[1]广州市皮肤病防治所皮肤科,广东广州510095 [2]广州市皮肤病防治所预防保健科,广东广州510095

出　　处：《皮肤性病诊疗学杂志》2018年第4期235-239,共5页Journal of Diagnosis and Therapy on Dermato-venereology

基　　金：广州市科技攻关项目(编号:201300000166);广州市医药卫生科技重大项目(编号:20121A031001)

摘　　要：目的:调查并分析广州地区吸毒戒毒人群梅毒感染现况及其危险因素,以便加强对该人群梅毒防治工作。方法:通过方便抽样,组织广州地区吸毒和强制戒毒人员、社区美沙酮门诊戒毒人员,进行面对面健康教育,知情同意后填写结构式问卷收集其人口学特征及性行为学信息,采集血液,用TRUST和(或)TPPA检测梅毒抗体,SPSS 17.0分析资料。结果:共调查吸毒戒毒人员473例,发现梅毒感染者41例,梅毒感染率8.7%,梅毒知识知晓率为38.1%。单因素分析显示,女性[OR=2.49、95%CI(1.03~6.05)]、职业分布[OR=3.41,95%CI(1.32~8.89)]、偶尔使用安全套[OR=23.24,95%CI(8.90~60.81)]以及共用针具[OR=6.20,95%CI(3.37~11.49)]等4个因素与感染梅毒有关。多因素分析则发现性别、职业分布、安全套使用频率、吸毒方式以及吸毒年限5个因素与梅毒感染相关。结论:广州地区吸毒戒毒人群感染梅毒普遍,感染梅毒的危险因素与性别、吸毒方式等有关,需要结合实际开展梅毒防治工作。Objective：To analyze prevalence and risk factors of syphilis in drug users（DUs） in Guangzhou,China.Methods：A cross-sectional survey was performed in the study.Drug users who agreed to participate in the study were interviewed,health education was delivered,questionnaire survey was conducted,and free serum screen by both TRUST and TPPA was provided.Data was analyzed by SPSS 17.0.Results：Of 473 DUs included,the syphilis seroprevalence was8.7%,and awareness rate of syphilis-preventing knowledge was 38.1%.Analyse on syphilis infection single risk factors showed that risk factors associated with syphilis infection included females [OR = 2.49、95% CI（1.03 - 6.05） ]、occupation status[OR = 3.41,95% CI（1.32 -8.89） ],using condoms occasionally [OR = 23.24,95% CI（8.90 - 60.81） ] and needle sharing[OR = 6.20,95% CI（3.37 - 11.49） ].Binary logistic regression analyse showed gender,occupation,frequency of condom use,needle sharing,means of drug abuse,and years as a drug abuser may all associated with syphilis infection.Conclusion：The prevalence of syphilis infection among DUs in Guangzhou is common,and risk factors were also complex.Effective intervention steps should be taken to enhance syphilis prevention control in the subgroup of population.

关 键 词：梅毒 流行 吸毒 危险因素 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]