中药三联疗法对慢性盆腔炎血清炎性指标及血液流变学影响  

Effect of Traditional Chinese Medicine Triple Therapy on Serum Inflammatory Markers and Hemorheology in Chronic Pelvic Inflammatory Disease

作　　者：吴飞华[1] WU Fei-hua(Jiangxi Provincial Hospital of Traditional Chinese Medicine,Department of Gynecology,Nanchang Jiangxi 330006,China)

机构地区：[1]江西省中医院中医妇科，江西 南昌 330006

出　　处：《药品评价》2018年第18期47-49,53,共4页Drug Evaluation

摘　　要：目的:探讨中药三联疗法对慢性盆腔炎血清炎性指标及血液流变学的影响,进而指导临床应用。方法:选取我院2016年3月—2018年3月收治的慢性盆腔炎患者124例,所有患者按照数字随机分组原则分为西医组和中医组各62例,西药组患者给予头孢拉定胶囊口服+微波照射物理治疗+替硝唑注射液灌肠三联疗法,中药组患者给予中药口服+中药热敷+中药灌肠三联疗法。结果:治疗后,西药组和中药组TNF-a、CRP、IL-1β以及IL-6均明显下降,与治疗前比较,差异显著(P<0.05);治疗后,中药组TNF-a、CRP、IL-1β以及IL-6均明显低于西药组,差异显著(P<0.05);治疗后,西药组和中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显下降,与治疗前比较,差异显著(P<0.05);治疗后,中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显低于西药组,差异显著(P<0.05)。结论:中药三联疗法可有效改善慢性盆腔炎患者血液流变学指标,缓解患者的炎性反应,临床应用价值较高。Objective： To investigate the effect of traditional Chinese medicine triple therapy on serum inflammatory markers and hemorheology in chronic pelvic in？ammatory disease, and to guide clinical application. Methods： A total of 124 patients with chronic pelvic in？ammatory disease admitted to our hospital from March 2016 to March 2018 were enrolled. All patients were divided into Western medicine group and Chinese medicine group according to the principle of numerical random grouping. The western medicine group was given cefradine capsule orally＋microwave. Irradiation physical therapy＋tinidazole injection enema triple therapy, Chinese medicine group patients with traditional Chinese medicine oral＋Chinese medicine hot compress＋Chinese medicine enema triple therapy. Results： After treatment, TNF-a, CRP, IL-1β and IL-6 were signi？cantly decreased in the Western medicine group and the Chinese medicine group （P〈0.05）. After treatment, the TNF-a, CRP IL-1β and IL-6 in Chinese medicine group were signi？cantly lower than the western medicine group （P〈0.05）. After treatment, the hematocrit, erythrocyte sedimentation rate, whole blood high-viscosity and whole blood low-cut viscosity of western medicine group and Chinese medicine group were signi？cantly improved compared with before treatment （P〈0.05）. After treatment, the hematocrit, erythrocyte sedimentation rate, whole blood high-viscosity and whole blood low-cut viscosity of Chinese medicine group were significantly lower than that of western medicine group （P〈0.05）. Conclusion： Traditional Chinese medicine triple therapy can effectively improve the blood rheology index of patients with chronic pelvic in？ammatory disease, relieve the in？ammatory response of patients, and increase the clinical application value.

关 键 词：中药内服 中药热敷 中药灌肠 慢性盆腔炎 炎性指标 血液流变学 

分 类 号：R271[医药卫生—中医妇科学]