根治性手术治疗对Ⅰb2～Ⅱb期宫颈恶性肿瘤的疗效预后分析  

Prognostic analysis of radical surgery for stage Ⅰb2-Ⅱb cervical cancer

作　　者：张婷 龙雯晴[2] 沈育红[2] 吴步初[2] ZHANG Ting;LONG Wenqing;SHEN Yuhong;WU Buchu(Department of Obstetrics and Gynecology,North Hospital of Ruijin Hospital Affiliated to Shanghai Jiaotong University Medical College,Shanghai 201801,China;Department of Obstetrics and Gynecology,Ruijin Hospital Affiliated to Shanghai Jiaotong University Medical College,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院北院妇产科,上海201801 [2]上海交通大学医学院附属瑞金医院妇产科,上海200025

出　　处：《中国医药科学》2018年第16期184-188,共5页China Medicine And Pharmacy

摘　　要：目的探讨根治性手术治疗对Ⅰb2～Ⅱb期宫颈恶性肿瘤的疗效预后影响及影响晚期宫颈恶性肿瘤相关危险因素。方法回顾分析2003年1月1日～2011年12月31日收治于上海交通大学附属瑞金医院妇科病房的70例Ⅰb2～Ⅱb期宫颈恶性肿瘤患者临床资料,并对其预后相关影响因素进行分析。结果 (1)平均年龄为(47.77±10.03)岁。(2)单因素分析表明:临床分期、淋巴结转移、宫旁浸润是影响宫颈恶性肿瘤预后的相关因素(P <0.05),术前治疗(P=0.166)不是影响宫颈恶性肿瘤预后的相关因素。多因素回归分析表明:淋巴结转移(P=0.020)是影响宫颈恶性肿瘤预后的独立危险因素。结论影响宫颈癌的预后因素有临床分期、淋巴结的转移、宫旁浸润,其中淋巴结转移是影响宫颈癌的重要独立预后因素,而接受新辅助治疗与宫颈癌的预后无关。Objective To investigate the effect and prognosis of radical surgery on stage Ⅰb2-Ⅱb cervical malignancies and the related risk factors of advanced cervical malignancies. Methods The clinical data of 70 patients with stage Ⅰb2-Ⅱb cervical malignancies in the gynecological ward of Ruijin Hospital Affiliated to Shanghai Jiaotong University from January 1, 2003 to December 31, 2011 were retrospectively analyzed, and the related prognostic factors were analyzed. Results （1）The average age was （47.77 ± 10.03） years.（2） Univariate analysis showed that clinical stage, lymph node metastasis and parametrial infiltration were the related factors affecting the prognosis of cervical malignant tumors （P 〈 0.05）. Preoperative treatment （P=0.166） was not the related factor affecting the prognosis of cervical malignant tumors. Multivariate regression analysis showed that lymph node metastasis （P=0.020） was an independent risk factor for the prognosis of cervical cancer. Conclusion The prognostic factors of cervical cancer are clinical stage, lymph node metastasis and parametrial infiltration. Lymph node metastasis is an important independent prognostic factor of cervical cancer, and neoadjuvant therapy is not related to the prognosis of cervical cancer.

关 键 词：宫颈恶性肿瘤 临床分期 新辅助治疗 预后因素 

分 类 号：R711.74[医药卫生—妇产科学]