埃博拉病毒经气溶胶感染与传播的研究进展  

Advances in research on the aerosol infection and transmission of Ebola virus

作　　者：王中一 聂鑫[2] 郭振东 李京京 程洪亮 靳晓军 刘林娜 钱军 陆兵 WANG Zhong-yi;NIE Xin;GUO Zhen-dong;LI Jing-jing;CHENG Hong-liang;JIN Xiao-jun;LIU Lin-na;QIAN Jun;LU Bing(Academy of Military Medical Sciences,Academy of Military Sciences,Beiji,g 100850,Chi,a;No.65316 Unit of PLA)

机构地区：[1]军事科学院军事医学研究院 [2]中国人民解放军65316部队

出　　处：《中国病原生物学杂志》2018年第8期914-916,共3页Journal of Pathogen Biology

基　　金：国家重点研发计划"生物安全关键技术研发"重点专项(No.2016YFC1202600)

摘　　要：埃博拉病毒是一种可在人类及非人灵长类间通过接触传播的烈性病原微生物,致死率高达90%。目前关于埃博拉病毒能否在人际间经气溶胶传播,还未有定论。但经过多年研究表明,在实验室内,埃博拉病毒可通过气溶胶感染非人灵长类,极低剂量即可引起致命性感染。并且埃博拉病毒在动物间的气溶胶传播在实验室内已被证实。除此之外,埃博拉病毒变异速度惊人,不排除可导致大面积暴发的可能性。Ebola virus disease has a fatality rate is as high as 90%and virus can be transmitted by contact between humans and non-human primates.There has been no definitive agreement on whether Ebola virus can be transmitted by aerosol.However,years of research have indicated that in the laboratory,Ebola virus can infect non-human primates by aerosol and extremely low doses can lead to fatal infections.Moreover,the transmission of Ebola virus among animals has been confirmed in the laboratory.In addition,Ebola virus has a remarkable rate of mutation,which does not rule out the possibility of widespread outbreaks.Researchers should focus on routes of Ebola virus transmission,its ability to spread across species,and new aspects and properties of the virus.

关 键 词：埃博拉病毒病 感染与传播方式 气溶胶 遗传变异 综述 

分 类 号：R379.5[医药卫生—病原生物学]