美沙酮维持治疗患者退出风险及影响因素  

Risks and its influential factors among patients dropped out from methadone treatment in Jiangsu province

作　　者：陈国红[1] 向婷 耿光伟 周静芳[4] 杨的松[4] 周开兰 周明生 徐永康[7] 孙庆元[8] CHEN Guo-hong;XIANG Ting;GENG Guang-wei;ZHOU Jing-fang;YANG Di-song;ZHOU Kai-lan;ZHOU Ming-sheng;XU Yong-kang;SUN Qing-yuan(Jiangsu Province Center for Disease Control and Prevention,Nanjing 210009,China)

机构地区：[1]江苏省疾病预防控制中心,江苏南京210009 [2]南京市朝天宫社区卫生服务中心 [3]南京市职业病防治院 [4]无锡市疾病预防控制中心 [5]无锡市山北街道社区卫生服务中心 [6]常州市常武太湖医院 [7]镇江市疾病预防控制中心 [8]连云港市第四人民医院

出　　处：《江苏预防医学》2018年第5期488-490,共3页Jiangsu Journal of Preventive Medicine

摘　　要：目的了解美沙酮维持治疗患者退出风险及影响因素。方法收集2006—2016年全省10个设区市19个美沙酮维持治疗门诊入组收治的7 493例海洛因成瘾患者治疗信息,对其人口学特征、治疗前吸毒状况、治疗后服药特征及退出治疗影响因素进行分析。结果 7 493例患者参加治疗时平均吸毒(9.64±4.66)年,注射吸毒占77.82%。2 328例(31.07%)患者治疗过程中至少退出1次并再次入组治疗,1年退出率为26.50%,3年退出率为49.40%,5年退出率为65.60%。Cox回归分析结果显示,南京市、汉族、曾经戒过毒、较高治疗剂量患者门诊治疗退出风险较低。结论美沙酮维持治疗门诊应加强对患者的综合干预及激励机制,鼓励患者坚持治疗。Objective To analyze risks and influential factors among patients dropped out from methadone treatment in Jiangsu province. Methods Medication information of 7 493 herorin addicts undertaking methadone treatment from 19 methadone treatment clinics were collected from network reports in 10 cities from 2006 to 2016. Demographic characteristics, heroin abuse information before entering treatment, medication characteristics after entering treatment and influential factors of dropping out treatment were analyzed. Results The average duration of heroin abuse before entering clinics was 9.64±4.66 years among 7 493 subjects, the injection drug use accounted for 77.82%.2 328 patients （31.07%） dropped out at least once and re-entered the treatment group. The 1-year quit rate was 26.50%, the 3-year quit rate was 49.40%, and the 5-year dropout rate was 65.60%. Cox regression analysis showed that patients in Nanjing, of Han ethnicity , with drug rehabilitation treatment history or higher dosage of treatment had lower dropout risks from outpatient clinics. Conclusion Methadone treatment clinics should reinforce comprehensive intervention and to set up incentive mechanics in order to encourage patients to persist in treatment.

关 键 词：美沙酮 维持治疗 海洛因成瘾者 退出风险 

分 类 号：R512.91[医药卫生—内科学]