小儿肥胖与阻塞性睡眠呼吸暂停低通气综合征关系分析  

Relationship Between Obstructive Sleep Apnea Hypopnea Syndrome in Children

作　　者：陈冬梅[1] 魏萍[1] 杨文庆[1] 李淑闽[1] Chen Dongmei;Wei Ping;Yang Wenqing;Li Shumin(The Second People＇s Hospital of Fujian University of Traditional Chinese Medicine,Fuzhou,35000)

机构地区：[1]福建中医药大学附属第二人民医院,福州350003

出　　处：《世界睡眠医学杂志》2018年第8期926-929,共4页World Journal of Sleep Medicine

摘　　要：目的:探讨小儿肥胖与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)关系。方法:选取2015年6月至2018年6月福建中医药大学附属第二人民医院儿科门诊收治的单纯性肥胖患儿130例作为观察组,选择同期在同一医院进行健康体检的儿童130例作为对照组,给予2组儿童体格检查、影像学检查、多导睡眠监测,比较2组儿童的OSAHS发生率、BMI标准值、AHI、OAI、MSa O2、LSa O2、CAI、睡眠效率,扁桃体肥大与腺样体肥大情况,分析肥胖、扁桃体肥大、腺样体肥大与OSAHS、AHI、OAI、LSa O2之间的相关性。结果:观察组OSAHS发生率为59.23%(77/130),显著高于对照组的26.15%(34/130)(P<0.05);观察组BMI标准值、AHI、OAI、CAI均显著高于对照组,LSa O2、MSa O2、睡眠效率均显著低于对照组(P<0.05);OSAHS组与非OSAHS组在性别分布、年龄等差异无统计学意义(P>0.05),OSAHS组BMI Z值、肥胖数、扁桃体肥大数与腺样体肥大数均显著高于非OSAHS组(P<0.05);多因素回归分析显示,肥胖、扁桃体肥大、腺样体肥大与儿童OSAHS的发生、AHI均有显著的正相关性,与LSa O2有显著的负相关性(P<0.01)。结论:小儿肥胖与睡眠呼吸综合征存在显著相关性,是重要的致病危险因子,临床上要重视对肥胖儿童的OSAHS临床症状与PSG监测,做到早预防、早发现、早治疗。Objective： To investigate the relationship between childhood obesity and obstructive sleep apnea hypopnea syndrome（ OSAHS）. Methods： From June 2015 to June 2018,130 children with simple obesity were selected as observation group and 130 children who underwent physical examination in the same hospital as control group. Physical examination,imaging examination,polysomnography and polysomnography were given to the two groups. The incidence of OSAHS in the two groups was compared with AHIOOAI,MSa O2,LSa O2 CAI,sleep efficiency,tonsil hypertrophy and adenoid hypertrophy,and obesity and tonsil hypertrophy were analyzed. The correlation between adenoid hypertrophy and OSAHS AHIOAIN LSa O2. Results： The incidence of OSAHS in the observation group was 59. 23%（ 77/130）,which was significantly higher than that in the control group（ 26. 15%,34/130）（ P〈0. 05）,the standard value of BMI in the observation group was significantly higher than that in the control group（ P〈0. 05）,and the sleep efficiency was significantly lower than that in the control group（ P〈0. 05）. There was no significant difference in sex distribution and age between the OSAHS group and the non OSAHS group（ P〈0. 05）. The number of obesity,tonsil hypertrophy and adenoid hypertrophy were significantly higher than those of the control group（ P〈0. 05）,the multivariate regression analysis showed that there was a significant positive correlation between obesity,tonsil hypertrophy,adenoid hypertrophy and the occurrence of OSAHS in children（ P〈0. 05）. There was a significant negative correlation with LSa O2（ P〈0. 01）.Conclusion： There is a significant correlation between obesity and sleep respiratory syndrome in children,which is an important risk factor. Clinical attention should be paid to monitoring the clinical symptoms of OSAHS and PSG in obese children so as to prevent early,discover early and treat early.

关 键 词：小儿肥胖 睡眠呼吸暂停综合征 多导睡眠监测 相关性分析 

分 类 号：R725.6[医药卫生—儿科]